Dr. Adam Dicker, MD

• Medical Oncology

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• Thomas Jefferson University Hospitals

  Residency Hospital

• Massachusetts General Hospital

  Internship Hospital

• Harvard Medical School

  Medical School, 2006

• Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model, 2017-03-28

• Multidisciplinary Intervention of Early, Lethal Metastatic Prostate Cancer: Report From the 2015 Coffey-Holden Prostate Cancer Academy Meeting, 2015-10-19

• Transcriptomic Heterogeneity of Gleason Grade Group 5 Prostate Cancer, 2020-05-24

• Hematologic toxicity of concurrent administration of Radium-223 and next generation anti-androgen therapies, 2015-01-23

• AR function in promoting metastatic prostate cancer, 2015-05-16

• Prospective study to define the clinical utility and benefit of Decipher testing in men following prostatectomy, 2019-11-12

• Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences, 2021-06-03

• CDK7 inhibition suppresses Castration-Resistant Prostate Cancer through MED1 inactivation, 2019-08-29

• DNA-PKcs mediated transcriptional regulation drives prostate cancer progression and metastasis, 2015-07-13

• A Phase I Study of the Combination of Sorafenib With Temozolomide and Radiation Therapy for the Treatment of Primary and Recurrent High-Grade Gliomas, 2012-06-09

• A comparative study of PCS and PAM50 prostate cancer classification schemes, 2021-02-02

• Development and Validation of a Prostate Cancer Genomic Signature that Predicts Early ADT Treatment Response Following Radical Prostatectomy, 2018-05-14

• The Financial Impact of Hypofractionated Radiation for Localized Prostate Cancer in the United States, 2019-01-02

• Decipher identifies men with otherwise clinically favorable-intermediate risk disease who may not be good candidates for active surveillance, 2019-08-27

• Performance of Clinicopathologic Models in Men with High Risk Localized Prostate Cancer: Impact of a 22-Gene Genomic Classifier, 2020-03-30

• Evaluating the Clinical Impact of a Genomic Classifier in Prostate Cancer Using Individualized Decision Analysis, 2015-04-02

• Bone Health Management in the Continuum of Prostate Cancer Disease, 2022-09-02

• Impact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer, 2018-07-24

• Genomic Prostate Cancer Classifier Predicts Biochemical Failure and Metastases in Patients After Postoperative Radiation Therapy, 2014-07-08

• Phase I Trial of Weekly Cabazitaxel with Concurrent Intensity Modulated Radiation and Androgen Deprivation Therapy for the Treatment of High-Risk Prostate Cancer, 2020-02-03

• RB/E2F1 as a master regulator of cancer cell metabolism in advanced disease, 2021-04-20

• High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program, 2019-09-25

• Adding Short-Term Androgen Deprivation Therapy to Radiation Therapy in Men With Localized Prostate Cancer: Long-Term Update of the NRG/RTOG 9408 Randomized Clinical Trial, 2021-09-01

• A hormone-DNA repair circuit governs the response to genotoxic insult, 2013-09-11

• Clinical and Genomic Characterization of Low-Prostate-specific Antigen, High-grade Prostate Cancer, 2018-02-22

• The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness, 2014-08-27

• Impact of radiation therapy dose escalation on prostate cancer outcomes and toxicities, 2020-10-17

• Diffusing alpha-emitters radiation therapy in combination with temozolomide or bevacizumab in human glioblastoma multiforme xenografts, 2022-09-27

• Innate Immune System in the Context of Radiation Therapy for Cancer, 2023-08-04

• AXIN2Expression Predicts Prostate Cancer Recurrence and Regulates Invasion and Tumor Growth, 2016-01-15

• Impact of Decipher on use of post-operative radiotherapy: Individual patient analysis of two prospective registries, 2021-01-24

• A paradigm shift from anatomic to functional and molecular imaging in the detection of recurrent prostate cancer, 2019-05-01

• Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer, 2017-11-29

• Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-dependent SMAC Mediated Apoptotic Response in Non-Small Cell Lung Cancer, 2018-01-08

• Characterization of 1,577 Primary Prostate Cancers Reveals Novel Biological and Clinicopathological Insights into Molecular Subtypes, 2015-05-08

• SYSTEMATIC REVIEW OF HYPOFRACTIONATED RADIATION THERAPY FOR PROSTATE CANCER, 2013-03-01

• TOP2A and EZH2 provide early detection of an aggressive prostate cancer subgroup, 2017-09-12

• Prostate cancer in young men represents a distinct clinical phenotype: gene expression signature to predict early metastases, 2021-03-09

• Integrated classification of prostate cancer reveals a novel luminal subtype with poor outcome, 2016-06-14

• ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma, 2013-09-21

• Improvement in Therapeutic Efficacy and Reduction in Cellular Toxicity: Introduction of a Novel Anti-PSMA-Conjugated Hybrid Antiandrogen Nanoparticle, 2018-04-04

• Stromal Gene Expression is Predictive for Metastatic Primary Prostate Cancer, 2017-03-19

• Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease, 2017-03-30

• Performance of a Prostate Cancer Genomic Classifier in Predicting Metastasis in Men with Prostate-specific Antigen Persistence Postprostatectomy, 2017-12-10

• Novel actions of next-generation taxanes benefit advanced stages of prostate cancer, 2015-02-15

• Low PCA3 expression is a marker of poor differentiation in localized prostate tumors: exploratory analysis from 12,076 patients, 2017-02-07

• Transcriptomic heterogeneity of androgen receptor (AR) activity defines ade novolow AR-active subclass in treatment naive primary prostate cancer, 2019-09-12

• Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2, 2019-12-16

• Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer, 2018-10-26

• ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer, 2019-02-14

• RB Loss Promotes Prostate Cancer Metastasis, 2016-12-06

• Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer, 2020-10-09