Dr. Allan Friedman, MD

• Neurosurgery

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• University Western Ontario

  Fellowship Hospital, 1981

• Duke University Medical Center

  Residency Hospital, 1978

• Duke University Medical Center

  Internship Hospital, 1975

• Eastern Illinois University

  Medical School, 1974

• English

• German

• FrequentATRX,CIC,FUBP1andIDH1mutations refine the classification of malignant gliomas, 2012-08-03

• Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma, 2009-06-28

• Fourth Ventricular Schwannoma: Identical Clinicopathologic Features as Schwann Cell-Derived Schwannoma with Unique Etiopathologic Origins, 2011-12-13

• Single-institution retrospective review of patients with recurrent glioblastoma treated with bevacizumab in clinical practice, 2019-02-13

• Co-localization of gadolinium-DTPA with high molecular weight molecules after intracerebral convection-enhanced delivery in man, 2011-05-17

• Second Case of Tumors Associated With Heterozygous NTHL1 Variant, 2022-07-11

• The genetic landscape of anaplastic astrocytoma, 2013-10-16

• Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy, 2010-09-19

• Treatment of neuroinflammation by soluble tumor necrosis factor receptor Type II fused to a thermally responsive carrier Laboratory investigation, 2009-07-29

• MiR-215 is induced post-transcriptionally via HIF-Drosha complex and mediates glioma-initiating cell adaptation to hypoxia by targeting KDM1B, 2016-01-11

• Phase II study of carboplatin, irinotecan and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy1, 2011-05-16

• Bevacizumab Plus Irinotecan in Recurrent WHO Grade 3 Malignant Gliomas, 2008-11-01

• Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy, 2021-01-13

• A Novel Method for Volumetric MRI Response Assessment of Enhancing Brain Tumors, 2011-01-26

• Severe adverse immunologic reaction in a patient with glioblastoma receiving autologous dendritic cell vaccines combined with GM-CSF and dose-intensified temozolomide, 2014-11-11

• A Novel, Reproducible, and Objective Method for Volumetric Magnetic Resonance Imaging Assessment of Enhancing Glioblastoma, 2014-07-18

• A Review of VEGF/VEGFR-Targeted Therapeutics for Recurrent Glioblastoma, 2011-12-07

• Mutations inIDH1,IDH2, and in theTERTpromoter define clinically distinct subgroups of adult malignant gliomas, 2014-01-28

• MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation, 2019-04-30

• Malignant brainstem gliomas in adults: clinicopathological characteristics and prognostic factors, 2014-05-17

• Exome sequencing identifies somatic gain-of-functionPPM1Dmutations in brainstem gliomas, 2014-06-01

• Worse outcomes for patients undergoing brain tumor and cerebrovascular procedures following the ACGME resident duty-hour restrictions, 2014-06-13

• Intraoperative microseizure detection using a high-density micro-electrocorticography electrode array, 2022-05-27

• An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme, 2010-03-01

• Tetanus toxoid and CCL3 improve DC vaccines in mice and glioblastoma patients, 2015-03-11

• Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy, 2009-06-17

• Dendritic cells enhance polyfunctionality of adoptively transferred T cells which targetcytomegalovirusin glioblastoma, 2017-11-01

• Oncolytic Polio Virotherapy of Cancer, 2014-06-17

• Mismatch Repair Deficiency Does Not Mediate Clinical Resistance to Temozolomide in Malignant Glioma, 2008-08-01

• Long-term Survival in Glioblastoma withCytomegaloviruspp65-targeted Vaccination, 2017-04-15

• The genomic landscape ofTERTpromoter wildtype-IDHwildtype glioblastoma, 2018-05-25

• A Pilot Study of IL-2Ra Blockade during Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with Glioblastoma, 2012-02-27