Dr. Bruce Clurman, PHD

• Medical Oncology

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• Fred Hutchinson Cancer Res Center

  Residency Hospital

• English

• French

• Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in Glioblastoma stem-like cells, 2015-12-07

• A Mechanism Misregulating p27 in Tumors Discovered in a Functional Genomic Screen, 2007-12-07

• Cand1 Promotes Assembly of New SCF Complexes Through Dynamic Exchange of F-box Proteins, 2013-02-28

• Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice, 2019-04-02

• Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations, 2022-02-28

• The miR-106a~363Xpcl1miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27Kip1cell cycle inhibitor, 2017-04-07

• Fbw7/hCDC4 dimerization regulates its substrate interactions, 2007-02-13

• Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12, 2021-04-06

• DGCR8 mediates repair of UV-induced DNA damage independently of RNA processing, 2017-04-04

• Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and ß-TrCP, 2019-01-28