Dr. Hans C Oettgen, MD

• Allergy & Immunology

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• Boston Children's Hospital (allergy/immunology)

  Fellowship Hospital, 2013

• Boston Children's Hospital (allergy/immunology)|boston Children's Hospital (immunology)

  Fellowship Hospital, 2013

• Boston Children's Hospital (immunology)

  Fellowship Hospital, 1994

• Boston Children's Hospital

  Residency Hospital, 1990

• Harvard Medical School

  Medical School, 1987

• Williams College

  Undergraduate School, 1980

• Regulatory T cell reprogramming towards a Th2 cell-like lineage impairs oral tolerance and promotes food allergy, 2015-03-10

• Immune Changes Beyond Th2 Pathways During Rapid Multifood Immunotherapy enabled with Omalizumab, 2021-05-29

• IgE and IgG Antibodies as Regulators of Mast Cell and Basophil Functions in Food Allergy, 2020-12-11

• Novel Presentation of Omenn Syndrome in Association with Aniridia, 2009-04-22

• IL-4 Production by Group 2 Innate Lymphoid cells Promotes Food Allergy by Blocking Regulatory T cell Function, 2016-04-18

• Omeprazole inhibits IgE-mediated mast cell activation and allergic inflammation induced by ingested allergen in mice, 2020-03-16

• IL-10 suppresses IL-17-mediated dermal inflammation and reduces the systemic burden of vaccinia virus in a mouse model of eczema vaccinatum, 2013-11-27

• Skin inflammation arising from cutaneous Treg deficiency leads to impaired viral immune responses, 2010-06-14

• Regulatory T cell-derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity, 2020-10-20

• An IgE receptor mimetic peptide (PepE) protects mice from IgE mediated anaphylaxis, 2013-10-31

• IgE receptor signaling in food allergy pathogenesis, 2015-09-18

• Inhibition of Immunoglobulin E signals during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells, 2014-07-10

• IgE promotes type 2 innate lymphoid cells in murine food allergy, 2018-01-22

• Polyclonal IgE Induces Mast Cell Survival and Cytokine Production, 2009-06-25

• Food allergy: Insights into etiology, prevention and treatment provided by murine models, 2014-02-14

• IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling, 2010-12-17

• A humanized mouse model of anaphylactic peanut allergy, 2016-06-08

• Allergen-specific IgG antibodies signaling via Fc?RIIb promote food tolerance, 2017-05-04

• In vivo Regulation of the Allergic Response by the Interleukin 4 Receptor Alpha Chain Immunoreceptor Tyrosine-based Inhibitory Motif, 2010-04-14

• Allergen-Specific IgA Antibodies Block IgE-Mediated Activation of Mast Cells and Basophils, 2022-07-05

• Lyn Kinase Controls Basophil GATA-3 Transcription Factor Expression and Induction of Th2 Cell Differentiation, 2009-04-09

• Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy, 2012-11-14

• Tissue-Specific Expression of the Low-Affinity IgG Receptor, Fc?RIIb, on Human Mast Cells, 2018-06-06

• Oral immunotherapy induces IgG antibodies that act via Fc?RIIb to suppress IgE-mediated hypersensitivity, 2014-07-16

• IgE INFLUENCES THE NUMBER AND FUNCTION OF MATURE MAST CELLS BUT NOT PROGENITOR RECRUITMENT IN ALLERGIC PULMONARY INFLAMMATION1, 2009-02-15

• High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy, 2021-10-19

• Fifty years later: Emerging functions of IgE antibodies in host defense, immune regulation, and allergic diseases, 2016-05-20

• Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food anaphylaxis, 2013-02-08

• A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis, 2012-11-30

• Preventing Asthma in High Risk Kids (PARK) with Omalizumab: Design, Rationale, Methods, Lessons Learned and Adaptation, 2020-11-24

• IgE blockade during food allergen ingestion enhances the induction of inhibitory IgG antibodies, 2018-11-04

• The soluble isoform of human Fc?RI is an endogenous inhibitor of IgE-mediated mast cell responses, 2018-11-20