Dr. Jeffrey Miller, MD

• Hematology

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Northwestern University Feinberg School Of Medicine

  Medical School, 2005

• University Of Minnesota

  Fellowship Hospital, 1991

• University Of Iowa Hospitals & Clinics

  Residency Hospital, 1988

• A Randomized Trial of One vs. Two Doses of Influenza Vaccine Following Allogeneic Transplantation, 2012-08-29

• iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti-PD-1 therapy, 2020-11-04

• Recipient T cell Exhaustion and Successful Adoptive Transfer of Haploidentical Natural Killer Cells, 2017-11-29

• DonorKIR BGenotype Improves Progression Free Survival of Non-Hodgkin lymphoma Patients Receiving Unrelated Donor Transplantation, 2016-05-21

• The Past, Present, and Future of NK Cells in Hematopoietic Cell Transplantation and Adoptive Transfer, 2018-03-21

• New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer, 2012-03-15

• Peritoneal NK cells are responsive to IL-15 and percentages are correlated with outcome in advanced ovarian cancer patients, 2018-10-05

• The Phenotypic and Functional Characteristics of Umbilical Cord Blood and Peripheral Blood Natural Killer Cells, 2009-10-22

• Reduced Intensity Conditioning Followed by Related and Unrelated Allografts for Hematologic Malignancies: Expanded Analysis and Long Term Follow-Up, 2018-08-01

• Introduction to the Reports from the National Cancer Institute 1st International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation, 2010-03-02

• Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant, 2017-09-20

• A trispecific killer engager molecule against CLEC12A effectively induces NK cell mediated killing of AML cells, 2020-10-23

• Clinical-scale production of cGMP compliant CD3/CD19 cell-depleted NK cells in the evolution of NK cell immunotherapy at a single institution, 2018-03-12

• The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT), 2014-02-07

• A Phase 1 Trial of CNDO-109-Activated Natural Killer Cells in Patients with High-risk Acute Myeloid Leukemia, 2018-03-27

• Adaptive single-KIR+NKG2C+NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia, 2022-11-01

• Recipient HLA-C Haplotypes and miRNA 148a/b Binding Sites Have No Impact on Allogeneic Hematopoietic Cell Transplantation Outcomes, 2016-10-13

• A HER2 Tri-Specific NK Cell Engager Mediates Efficient Targeting of Human Ovarian Cancer, 2021-08-08

• Regulatory T Cells: A Review of Manufacturing and Clinical Utility, 2022-01-11

• NK cells - From Bench to Clinic, 2011-11-02

• Prevention of GVHD by adoptive T regulatory therapy is associated with active repression of peripheral blood toll-like receptor-5 mRNA expression, 2013-11-01

• Human NK Cell Development: One Road or Many?, 2019-08-29

• CITN11-02 interim trial results: subcutaneous administration of recombinant human IL-15 (rhIL-15) is associated with expansion of peripheral blood CD56+ NK cells and CD8+ T cells, 2015-11-04

• Toll-Like Receptor-7 (TLR-7) Agonist Administered Subcutaneously in a Prolonged Dosing Schedule in Heavily Pretreated Recurrent Breast, Ovarian, and Cervix Cancers, 2010-09-05

• Clinical utility of natural killer cells in cancer therapy and transplantation, 2014-03-05

• Follicular lymphoma patients with KIR2DL2 and KIR3DL1 and their ligands (HLA-C1 and HLA-Bw4) show improved outcome when receiving rituximab, 2019-03-12

• Epigenetic regulation of NK cell differentiation and effector functions, 2013-02-28

• Prolonged Subcutaneous Administration of 852A, a Novel Systemic Toll-like Receptor 7 Agonist, to Activate Innate Immune Responses in Patients with Advanced Hematologic Malignancies, 2012-06-20

• High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation, 2010-04-12

• Intraperitoneal delivery of human natural killer cells for treatment of ovarian cancer in a mouse xenograft model, 2013-08-27

• Advances in NK cell therapy for brain tumors, 2023-02-15

• Decreased Infections in Recipients of Unrelated Donor Hematopoietic Cell Transplantation from Donors with an Activating KIR Genotype, 2010-03-01

• Matching at HLA-C improved the outcomes after double umbilical cord blood transplantation for recipients of 2-4/6 HLA-matched grafts, 2016-10-29

• Ascorbic Acid PromotesKIRDemethylation During Early NK Cell Differentiation, 2020-08-05

• NK Cells and ?dT Cells for Relapse Protection After Allogeneic Hematopoietic Cell Transplantation (HCT), 2017-10-16

• Adaptive NK cells with low TIGIT expression are inherently resistant to myeloid-derived suppressor cells, 2016-08-08

• Identification of aKIRantisense lncRNA expressed by progenitor cells, 2013-07-18

• Natural Killer Cell Differentiation From Hematopoietic Stem Cells: A Comparative Analysis of Heparin and Stromal Cell Supported Methods, 2011-12-07

• CMV Triplex vaccine to enhance adaptive NK and T-cell reconstitution after autologous hematopoietic cell transplantation, 2022-03-08

• Early Adaptive NK Cell Expansion is Associated with Decreased Relapse After Autologous Transplant for Multiple Myeloma, 2020-12-17

• IL-15 Trispecific Killer Engagers (TriKEs) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function, 2016-02-04

• Adaptive NK cells resist regulatory T cell suppression driven by IL-37, 2018-05-21

• Phase 1 study of a bispecific ligand-directed toxin targeting CD22 and CD19 (DT2219) for refractory B-cell malignancies, 2015-03-15

• Unraveling Exhaustion in Adaptive and Conventional Natural Killer Cells, 2020-07-29

• Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker, 2016-09-16

• Natural Killer Cells Unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy, 2017-09-05

• Donor killer-cell immunoglobulin-like receptor (KIR) genotype does not improve graft-versus-leukemia responses in chronic lymphocytic leukemia (CLL) after unrelated donor transplant: a CIBMTR analysis, 2018-12-27

• Impact of ABO-Mismatch on Risk of Graft-versus-Host Disease after Umbilical Cord Blood Transplantation, 2013-02-18

• Impact of Cytomegalovirus (CMV) Reactivation After Umbilical Cord Blood Transplantation, 2009-09-26

• A tri-specific killer engager against mesothelin targets NK cells towards lung cancer, 2023-02-22

• Infusion Reactions in Natural Killer Cell Immunotherapy: A Retrospective Review, 2021-05-09

• Near complete response to Pembrolizumab in microsatellite-stable metastatic sebaceous carcinoma, 2018-06-19

• Massive ex vivo expansion of human natural regulatory T cells (Tregs) with minimal loss of in vivo functional activity, 2011-05-18

• Regulation of adaptive NK cells and CD8 T cells by HLA-C correlates with allogeneic hematopoietic cell transplantation and with CMV reactivation, 2015-09-28

• CD56dimCD57+NKG2C+NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT, 2015-09-29

• Use of natural killer cells as immunotherapy for leukaemia, 2008-10-14

• Umbilical Cord Blood T cells Express Multiple Natural Cytotoxicity Receptors After IL-15 Stimulation, but Only NKp30 Is Functional, 2008-10-01

• NCI 1st International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-tumor/leukemia Reaction, 2010-02-10

• Interleukin-15 Complex Treatment Protects Mice from Cerebral Malaria by Inducing Interleukin-10-Producing Natural Killer Cells, 2018-04-03

• Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma, 2022-11-29

• A First-in-Human Phase 1 Study of Subcutaneous Outpatient Recombinant Human IL-15 (rhIL-15) in Adults with Advanced Solid Tumors, 2017-12-04

• NCI 1st International Workshop on the Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Summary and Recommendations from the Organizing Committee, 2011-01-09

• Expression and Function of The TNF-Superfamily Receptor DR3 in Human Group 3 Innate Lymphoid Cells, 2015-06-22

• Adaptive NK cell and KIR-expressing T cell responses are induced by CMV and are associated with protection against CMV reactivation after allogeneic donor hematopoietic cell transplantation, 2015-06-06

• Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models, 2018-02-13

• Therapeutic effect of TRC105 and decitabine combination in AML xenografts, 2020-10-13

• Fewer Circulating Natural Killer Cells 28 Days After Double Cord Blood Transplantation Predicts Inferior Survival and IL-15 Response, 2016-10-30

• Donor killer-cell immunoglobulin-like receptorBhaplotypes, recipient HLA-C1 and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia, 2014-04-18

• Proceedings from the Fourth Haploidentical Stem Cell Transplantation Symposium - HAPLO2016, San Diego, California, December 1, 2016, 2018-01-12

• Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer, 2022-04-12

• A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer, 2010-09-20

• Potent Cytolytic Activity and Specific IL15 Delivery in a 2ndGeneration Trispecific Killer Engager, 2020-07-13

• Human CMV-induced Memory-like NKG2C+NK cells are Transplantable and Expand in vivo in Response to Recipient CMV Antigen, 2012-10-17

• Optimization of cGMP Purification and Expansion of Umbilical Cord Blood-Derived T-Regulatory Cells in Support of First-in-Human Clinical Trials, 2016-11-22

• Monocyte subpopulation recovery as predictors of hematopoietic cell transplantation outcomes, 2019-01-06

• Early Lymphocyte Recovery and Outcomes after Umbilical Cord Blood Transplantation (UCBT) for Hematologic Malignancies, 2010-09-08

• Natural Killer Cell Adoptive Transfer Therapy: Exploiting the First Line of Defense Against Cancer, 2016-02-17

• Presence of donor-encoded centromeric KIR B content increases the risk of infectious mortality in recipients of myeloablative, T cell deplete, HLA-matched HCT to treat AML, 2020-03-13

• Harnessing Features of Adaptive NK Cells to Generate iPSC-Derived NK Cells for Enhanced Immunotherapy, 2021-09-09

• Following transplantation for AML, donorKIR Cen B02better protects against relapse thanKIR Cen B01, 2021-06-11

• HLA-Bw4-I-80 Isoform Differentially Influences Clinical Outcome As Compared to HLA-Bw4-T-80 and HLA-A-Bw4 Isoforms in Rituximab or Dinutuximab-Based Cancer Immunotherapy, 2017-06-12

• Isolation and Characterization of Canine Natural Killer Cells, 2013-06-28

• Absence of early HHV-6 reactivation after cord blood allograft predicts powerful graft-versus-tumor effect, 2018-05-14

• Human effectors of acute and chronic GVHD overexpress CD83 and predict mortality, 2023-03-14

• Cytokine-induced memory-like natural killer cells have enhanced function, proliferation, andin vivoexpansion against ovarian cancer cells, 2019-01-15

• Targeting Natural Killer cells to Acute Myeloid Leukemiain vitrowith a CD16x33 bispecific killer cell engager (BiKE) and ADAM17 inhibition, 2013-05-20

• Dendritic cell recovery predicts better survival after umbilical cord blood transplantation, 2017-07-17

• Anti-HLA Antibodies in Double Umbilical Cord Blood Transplantation, 2011-05-03

• PHASE I TRIAL OF ALT-803, A NOVEL RECOMBINANT INTERLEUKIN-15 COMPLEX, IN PATIENTS WITH ADVANCED SOLID TUMORS, 2018-07-25

• Human Natural Killer Cell microRNA: Differential Expression ofMIR181A1B1andMIR181A2B2Genes Encoding Identical Mature microRNAs, 2014-11-20

• Generation of BiKEs and TriKEs to improve NK cell-mediated targeting of tumor cells, 2018-02-18

• Early reconstitution of NK and ?d T cells and its implication for the design of post-transplant immunotherapy, 2018-03-02

• Transcriptome Analysis of GVHD Reveals Aurora Kinase A as a Targetable Pathway for Disease Prevention, 2015-11-25

• CXCR4 Expression in CD34+ Cells and Unit Predominance after Double Umbilical Cord Blood Transplantation, 2012-09-07

• Characterization of a weakly expressedKIR2DL1variant reveals a novel upstream promoter that controls KIR expression, 2014-07-03

• NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo, 2020-09-18

• Functional NK cell repertoires are maintained through IL-2Ra and FasL, 2014-03-14

• miR-181 promotes human NK cell development by regulating Notch signaling, 2011-11-14

• Haploidentical Natural Killer Cells Induce Remissions in Non-Hodgkin Lymphoma Patients With Low Levels of Immune-suppressor Cells, 2017-12-07

• ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial, 2018-04-05

• Different Patterns of Evolution in the Centromeric and Telomeric Regions of GroupAandBHaplotypes of the Human Killer Cell Ig-Like Receptor Locus, 2010-12-29

• Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation, 2021-07-22

• CITN11-02 interim trial results: subcutaneous administration of recombinant human IL-15 (rhil-15) is associated with robust expansion of peripheral blood CD56+ NK cells, 2014-11-06

• Allogeneic hematopoietic cell transplantation in morphologic leukemia-free aplastic state, 2017-07-19

• Impact of Allele Level HLA Mismatch on Outcomes in Recipients of Double Umbilical Cord Blood Transplantation, 2015-09-30

• Association between recipientTNFrs361525 and acute GVHD: Results from analysis of BMT CTN-0201 samples, 2018-03-07