Dr. Jeffrey Taub, MD

• Pediatric Hematology & Oncology

• Pediatrics

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Childrens Hospital Of Michigan

  Fellowship Hospital, 1994

• Childrens Hospital Of Michigan

  Residency Hospital, 1991

• Victoria Hospital

  Internship Hospital, 1988

• University Of Western Ontario, School Of Medicine

  Medical School, 1987

• Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy, 2020-12-18

• Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia, 2020-02-26

• Favorable Survival Maintained in Children Who Have Myeloid Leukemia Associated With Down Syndrome Using Reduced-Dose Chemotherapy on Children's Oncology Group Trial A2971 A Report From the Children's Oncology Group, 2012-03-05

• Gene Signature of High White Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia, 2016-08-18

• "FLipping” the Story: FLT3-Mutated Acute Myeloid Leukemia and the Evolving Role of FLT3 Inhibitors, 2022-07-13

• Valproic Acid Synergistically Enhances The Cytotoxicity of Clofarabine in Pediatric Acute Myeloid Leukemia Cells, 2012-04-05

• Pediatric Cancer Patients' Treatment-Related Distress and Longer-Term Anxiety: An Individual Differences Perspective, 2016-05-19

• Treatment Outcome in Older Patients with Childhood Acute Myeloid Leukemia, 2012-06-06

• Satisfaction with support versus size of network: Differential effects of social support on psychological distress in parents of pediatric cancer patients, 2015-06-17

• Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AMLex vivo, 2017-12-05

• Safety, Pharmacokinetics, and Pharmacodynamics of Panobinostat in Children, Adolescents, and Young Adults with Relapsed Acute Myeloid Leukemia, 2020-08-18

• Longitudinal study of parent caregiving self-efficacy and parent stress reactions with pediatric cancer treatment procedures, 2012-10-04

• CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells, 2014-08-01

• Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells, 2016-12-21

• Simultaneous cotargeting of ATR and RNA Polymerase I transcription demonstrates synergistic antileukemic effects on acute myeloid leukemia, 2019-11-01

• Effect of Body Mass Index on the Outcome of Children with Acute Myeloid Leukemia, 2012-05-30

• Inhibition of XPO 1 enhances cell death induced by ABT -199 in acute myeloid leukaemia via Mcl-1, 2018-09-14

• Mindfulness and dynamic functional neural connectivity in children and adolescents, 2017-09-05

• Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells, 2017-04-07

• Pathologic Features of Down Syndrome Myelodysplastic Syndrome and Acute Myeloid Leukemia A Report From the Children's Oncology Group Protocol AAML0431, 2019-08-20

• A Unique Role of GATA1s in Down Syndrome Acute Megakaryocytic Leukemia Biology and Therapy, 2011-11-16

• Targeting mitochondrial respiration for the treatment of acute myeloid leukemia, 2020-10-02

• Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models ofFLT3-Mutated Acute Myeloid Leukemia, 2022-09-03

• MECHANISMS OF SYNERGISTIC ANTILEUKEMIC INTERACTIONS BETWEEN VALPROIC ACID AND CYTARABINE IN PEDIATRIC ACUTE MYELOID LEUKEMIA, 2010-10-01

• Panobinostat Synergistically Enhances the Cytotoxic Effects of Cisplatin, Doxorubicin or Etoposide on High-Risk Neuroblastoma Cells, 2013-09-30

• Targeting ERK enhances the cytotoxic effect of the novel PI3K and mTOR dual inhibitor VS-5584 in preclinical models of pancreatic cancer, 2017-05-15

• Neurodevelopmental consequences of pediatric cancer and its treatment: applying an early adversity framework to understanding cognitive, behavioral, and emotional outcomes, 2017-12-22

• Acute Myeloid Leukemia Cells Harboring MLL Fusion Genes or with the Acute Promyelocytic Leukemia Phenotype Are Sensitive to the Bcl-2-selective Inhibitor ABT-199, 2014-02-17

• Obatoclax Potentiates the Cytotoxic Effect of Cytarabine on Acute Myeloid Leukemia Cells by Enhancing DNA Damage, 2014-10-02

• Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation, 2020-08-24

• Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy, 2014-08-28

• Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-mutated Acute Myeloid Leukemia, 2019-07-18

• The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML, 2021-06-07

• Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells, 2016-08-24

• Prognosis and management of acute myeloid leukemia in patients with Down syndrome, 2014-09-18

• Posttraumatic Stress Symptoms in Parents of Pediatric Cancer Patients: A Mediational Analysis, 2014-08-19

• Meditation reduces brain activity in the default mode network in children with active cancer and survivors, 2022-08-04

• Co-targeting of HDAC, PI3K, and Bcl-2 Results in Metabolic and Transcriptional Reprogramming and Decreased Mitochondrial Function in Acute Myeloid Leukemia, 2022-10-05

• Class I and Class II Histone Deacetylases Are Potential Therapeutic Targets for Treating Pancreatic Cancer, 2012-12-14

• The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T- cell acute lymphoblastic leukemia: A report from the Children's Oncology Group, 2009-04-02

• Targeting the Wee1 Kinase for Treatment of Pediatric Down Syndrome Acute Myeloid Leukemia, 2014-06-24

• Parent Caregiver Self-Efficacy and Child Reactions to Pediatric Cancer Treatment Procedures, 2013-12-30

• Overexpression of GATA1 Confers Resistance to Chemotherapy in Acute Megakaryocytic Leukemia, 2013-07-10

• Synergistic antitumor interactions between MK-1775 and panobinostat in preclinical models of pancreatic cancer, 2014-10-18

• Binding of released Bim to Mcl-1 is a mechanism of intrinsic resistance to ABT-199 which can be overcome by combination with daunorubicin or cytarabine in AML cells, 2016-04-21

• Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells, 2016-05-05

• Heritable variation at the chromosome 21 geneERGis associated with acute lymphoblastic leukemia risk in children with and without Down syndrome, 2019-07-11

• Gemtuzumab Ozogamicin Can Reduce Minimal Residual Disease in Patients With Childhood Acute Myeloid Leukemia, 2013-09-04

• Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells, 2017-02-08

• Clinical Trial Enrollment is Associated With Improved Follow-up Rates Among Survivors of Childhood Cancer, 2019-11-08

• Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome, 2019-07-11

• Panobinostat Enhances Cytarabine and Daunorubicin Sensitivities in AML Cells through Suppressing the Expression of BRCA1, CHK1, and Rad51, 2013-11-11

• Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis, 2023-04-28

• Pediatric acute myeloid leukemia with breast chloromas, 2023-03-15