Dr. John Detre, MD

• Neurology

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• Yale University

  Medical School, 1986

• Early Parental Care Is Important for Hippocampal Maturation: Evidence from Brain Morphology in Humans, 2009-07-09

• Single-Voxel1H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD+) in humans at 7T using a 32-channel volume coil, 2019-09-10

• Relations between BOLD fMRI-Derived Resting Brain Activity and Cerebral Blood Flow, 2012-09-21

• Function Lateralization via Measuring Coherence Laterality, 2009-04-05

• Age-Related Differences in Working Memory Deficits During Nicotine Withdrawal, 2013-03-18

• Heterogeneous increases of regional cerebral blood flow during preterm brain development: Preliminary assessment with pseudo-continuous arterial spin labeled perfusion MRI, 2016-12-14

• Improving the Robustness of Pseudo Continuous Arterial Spin Labeling to Off Resonance and Pulsatile Flow Velocity, 2016-10-23

• Arterial Spin Labeling Perfusion MRI in Pediatric Arterial Ischemic Stroke - Initial Experiences, 2009-03-23

• Developmental coupling of cerebral blood flow and fMRI fluctuations in youth, 2022-03-29

• Neural Substrates Associated with Weather-Induced Mood Variability: An Exploratory Study Using ASL Perfusion fMRI, 2013-05-31

• DAT Genotype Modulates Brain and Behavioral Responses Elicited by Cigarette Cues, 2008-08-13

• An Actively Decoupled Dual Transceiver Coil System for Continuous ASL at 7 T, 2016-06-16

• INFLUENCES OF TEMPORAL LOBE EPILEPSY AND TEMPORAL LOBE RESECTION ON OLFACTION, 2018-05-16

• Assessment of Uterine Artery Geometry and Hemodynamics in Human Pregnancy With 4D Flow MRI and Its Correlation With Doppler Ultrasound, 2018-11-03

• Structure Specific Analysis of the Hippocampus in Temporal Lobe Epilepsy, 2010-03-17

• Structural Correlation based Outlier Rejection (SCORE) algorithm for ASL time series, 2016-08-29

• Short-range connections in the developmental connectome during typical and atypical brain maturation, 2017-10-09

• Effects of the Insulin Sensitizer Metformin in Alzheimer's Disease: Pilot Data from a Randomized Placebo-Controlled Crossover Study, 2017-04-15

• Interaction between Nitric Oxide Synthase Inhibitor Induced Oscillations and the Activation Flow Coupling Response, 2009-11-10

• Decreased Ventral Striatal Activity with Impulse Control Disorders in Parkinson's Disease, 2010-08-15

• Post-conventional moral reasoning is associated with increased ventral striatal activity at rest and during task, 2017-08-02

• Perfusion alterations converge with patterns of pathological spread in TDP-43 proteinopathies, 2018-04-17

• Transcranial Optical Monitoring of Cerebrovascular Hemodynamics in Acute Stroke Patients, 2009-03-02

• Brain Entropy Mapping Using fMRI, 2014-03-21

• A High-Resolution Computational Atlas of the Human Hippocampus from Postmortem Magnetic Resonance Imaging at 9.4 Tesla, 2008-09-18

• Hippocampal Volumetry and Memory fMRI in Temporal Lobe Epilepsy, 2009-08-11

• Glutamate Imaging (GluCEST) Lateralizes Epileptic Foci in Non-Lesional Temporal Lobe Epilepsy, 2015-10-14

• Serotonin transporter genotype modulates functional connectivity between amygdala and PCC/PCu during mood recovery, 2013-10-31

• 3D-Accelerated, Stack-of-spirals Acquisitions and Reconstruction of Arterial Spin Labeling MRI, 2016-11-03

• Fusing functional signals by sparse canonical correlation analysis improves network reproducibility, 2017-10-05

• Transcranial optical monitoring of cerebral hemodynamics in acute-stroke patients during mechanical thrombectomy, 2019-04-08

• Task-Enhanced Arterial Spin Labeled Perfusion MRI Predicts Longitudinal Neurodegeneration in Mild Cognitive Impairment, 2018-11-06

• Absolute Cerebral Blood Flow Quantification with Pulsed Arterial Spin Labeling During Hyperoxia Corrected with the Simultaneous Measurement of the Longitudinal Relaxation Time of Arterial Blood, 2011-08-29

• Efficient coding in the economics of human brain connectomics, 2022-02-01

• Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease, 2021-04-09

• In VivoMeasurement of Glutamate Loss is Associated with Synapse Loss in a Mouse Model of Tauopathy, 2014-07-05

• Applications of Arterial Spin Labeled MRI in the Brain, 2012-01-13

• ARTERIAL SPIN LABELING PERFUSION PREDICTS LONGITUDINAL DECLINE IN SEMANTIC VARIANT PRIMARY PROGRESSIVE APHASIA, 2016-07-05

• Cerebellum anatomy predicts individual risk-taking behavior and risk tolerance, 2022-03-26

• A VBM study demonstrating ‘apparent' effects of a single dose of medication on T1-weighted MRIs, 2012-05-10

• Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology, 2021-10-24

• Non-Invasive Respiratory Impedance Enhances Cerebral Perfusion in Healthy Adults, 2017-02-16

• Skeletal muscle microvascular flow in progressive peripheral artery disease: Assessment with continuous arterial spin-labeling perfusion magnetic resonance imaging, 2009-06-23

• Cerebral blood flow response during bolus normal saline Infusion after ischemic stroke, 2019-08-13

• Brain substrates of early (4 h) cigarette abstinence: Identification of treatment targets, 2017-11-20

• Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients during Head of Bed Manipulation, 2014-03-20

• Rotated spiral RARE for high spatial and temporal resolution volumetric arterial spin labeling acquisition, 2020-09-12

• Acute baclofen diminishes resting baseline blood flow to limbic structures: A perfusion fMRI study, 2012-04-17

• Reproducibility of functional network metrics and network structure: A comparison of task-related BOLD, resting ASL with BOLD contrast, and resting cerebral blood flow, 2013-08-10

• Migraine with Aura Is Associated with an Incomplete Circle of Willis: Results of a Prospective Observational Study, 2013-07-26

• Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study, 2013-04-30

• Arterial spin labeling provides a reliable neurobiological marker of autism spectrum disorder, 2018-12-13

• Transit Delay and Flow Quantification in Muscle With Continuous Arterial Spin Labeling Perfusion-MRI, 2011-01-03

• FlywheelTools: Data Curation and Manipulation on the Flywheel Platform, 2021-06-22

• Reliability of arterial spin labeling derived cerebral blood flow in periventricular white matter, 2021-11-05

• Noninvasive Measurement of Cerebral Blood Flow and Blood Oxygenation Using Near-Infrared and Diffuse Correlation Spectroscopies in Critically Brain-Injured Adults, 2009-11-30

• Direct Visualization of Short Transverse Relaxation Time Component (ViSTa), 2013-06-22

• Comparison of 2D and 3D single-shot ASL perfusion fMRI sequences, 2012-11-07

• Integrating1H MRS and deuterium labeled glucose for mapping the dynamics of neural metabolism in humans, 2022-02-07

• In vivoGluCEST MRI: Reproducibility, background contribution and source of glutamate changes in the MPTP model of Parkinson's disease, 2018-02-13

• Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder, 2011-11-22

• Microvascular Perfusion Based on Arterial Spin Labeled Perfusion MRI as a Measure of Vascular Risk in Alzheimer's Disease, 2013-04-17

• High Resolution Mapping of Modafinil Induced Changes in Glutamate Level in Rat Brain, 2014-07-28

• Evaluation of Segmented 3D Acquisition Schemes for Whole-brain High-resolution Arterial Spin Labeling at 3T, 2014-09-26

• Spatially-enhanced clusterwise inference for testing and localizing intermodal correspondence, 2022-10-26

• Estimating regional cerebral blood flow using resting-state functional MRI via machine learning, 2019-11-19

• Association of Cerebral Blood Flow With Longitudinal Changes in Cerebral Microstructural Integrity in the Coronary Artery Risk Development in Young Adults (CARDIA) Study Cerebral Blood Flow and Longitudinal Changes in Cerebral Microstructural Integrity, 2022-09-12

• Design and methods of the NiCK study: neurocognitive assessment and magnetic resonance imaging analysis of children and young adults with chronic kidney disease, 2015-04-30

• Arterial Spin Labeling MRI: An Emerging Biomarker for Alzheimer's Disease and Other Neurodegenerative Conditions, 2013-04-17

• Two nights of recovery sleep restores hippocampal connectivity but not episodic memory after total sleep deprivation, 2020-05-29

• Heterogeneity of Functional Activation During Memory Encoding Across Hippocampal Subfields in Temporal Lobe Epilepsy, 2011-07-07

• A framework for informing segmentation of in vivo MRI with information derived from ex vivo imaging: Application in the medial temporal lobe, 2017-09-12

• ASL-BIDS, the brain imaging data structure extension for arterial spin labeling, 2022-09-06

• Direct Comparison of FDG-PET and ASL-MRI in Alzheimer's Disease, 2011-10-21

• 1H magnetic resonance spectroscopy of2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo, 2020-01-27

• Mapping the alterations in glutamate with GluCEST MRI in a mouse model of dopamine deficiency, 2016-10-16

• ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion, 2022-06-10

• Basilar Artery Lateral Displacement May Be Associated with Migraine with Aura, 2018-02-21

• Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort, 2011-02-08

• Estimation of Perfusion and Arterial Transit Time in Myocardium using Free-breathing Myocardial ASL with Navigator-echo, 2010-08-18

• Test-Retest Reliability of Arterial Spin Labeling with Common Labeling Strategies, 2010-08-24

• Voxel-wise intermodal coupling analysis of two or more modalities using local covariance decomposition, 2022-06-22

• Interictal cortical hyperresponsiveness in migraine is directly related to the presence of aura, 2013-01-28

• Response to Letter Regarding Article, "Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients During Head-of-Bed Manipulation”, 2014-07-17

• Magnetic Resonance Imaging of Glutamate, 2012-01-22

• Continuous Optical Monitoring of Cerebral Hemodynamics during Head-of-Bed Manipulation in Brain-Injured Adults, 2013-09-07

• Structural and functional asymmetry of medial temporal subregions in unilateral temporal lobe epilepsy: a 7T MRI study, 2019-01-21

• Longitudinal imaging reveals sub-hippocampal dynamics in glutamate levels associated with histopathologic events in a mouse model of tauopathy and healthy mice, 2017-02-03

• Serotonin transporter genotype modulates the association between depressive symptoms and amygdala activity among psychiatrically healthy adults, 2011-07-20

• Mapping the structural and functional network architecture of the medial temporal lobe using 7T MRI, 2017-11-20

• A Perfusion fMRI Study of the Neural Correlates of Sustained-Attention and Working-Memory Deficits in Chronic Traumatic Brain Injury, 2012-02-22

• Decomposing cerebral blood flow MRI into functional and structural components: A non-local approach based on prediction, 2014-11-01

• Neural Correlates of Post-Conventional Moral Reasoning: A Voxel-Based Morphometry Study, 2015-06-03

• Effect of Blood T1 Estimation Strategy on Arterial Spin Labeled Cerebral Blood Flow Quantification in Children and Young Adults with Kidney Disease, 2018-03-28

• Test-Retest Reliability of Resting Brain Small-World Network Properties across Different Data Processing and Modeling Strategies, 2023-05-19

• QSIPrep: An integrative platform for preprocessing and reconstructing diffusion MRI, 2021-06-21

• Perfusion Imaging of Fatigue and Time-on-Task Effects in Patients With Parkinson's Disease, 2022-06-10

• Recommended Implementation of Arterial Spin Labeled Perfusion MRI for Clinical Applications: A consensus of the ISMRM Perfusion Study Group and the European Consortium for ASL in Dementia, 2014-04-08

• Prefrontal Transcranial Direct Current Stimulation Alters Activation and Connectivity in Cortical and Subcortical Reward Systems: A tDCS-fMRI Study, 2014-01-22

• Ex vivoMRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology, 2021-12-14

• Perfusion has no effect on the in vivo CEST effect from Cr (CrCEST) in skeletal muscle, 2016-11-29

• Modulation of resting brain cerebral blood flow by the GABA B agonist, baclofen: A longitudinal perfusion fMRI study, 2011-02-17

• Imaging Brain Fatigue from Sustained Mental Workload: An ASL Perfusion Study of the Time-On-Task Effect, 2009-11-24

• Methylphenidate modulates sustained attention and cortical activation in survivors of traumatic brain injury: A perfusion fMRI study, 2011-12-28

• Disconnectome associated with progressive white matter hyperintensities in aging: a virtual lesion study, 2023-08-31

• White matter lesion penumbra shows abnormalities on structural and physiologic MRI in the CARDIA cohort, 2019-07-25

• Cerebral Pulsed Arterial Spin Labeling Perfusion Weighted Imaging Predicts Language and Motor Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy, 2020-09-25

• Whole-brain background-suppressed pCASL MRI with 1D-accelerated 3D RARE Stack-Of-Spirals readout, 2017-08-24

• Volumetric glutamate imaging (GluCEST) using 7T MRI can lateralize nonlesional temporal lobe epilepsy: A preliminary study, 2021-07-13

• Comparison of PASL, PCASL and background suppressed 3D PCASL in Mild Cognitive Impairment, 2017-07-24