Dr. Michael Bigham, MD

• Pediatric Critical Care Medicine

• Pediatrics

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• University Of Toledo College Of Medicine And Life Sciences

  Medical School, 2002

• Testing the Prognostic Accuracy of the Updated Pediatric Sepsis Biomarker Risk Model, 2014-01-29

• External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock, 2023-08-02

• Corticosteroids and Pediatric Septic Shock Outcomes: A Risk Stratified Analysis, 2014-11-11

• Differential expression of the Nrf2-linked genes in pediatric septic shock, 2015-09-17

• Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1, 2023-06-26

• Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray, 2011-11-18

• Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study, 2022-07-11

• Proprotein Convertase Subtilisin/Kexin Type 9 Loss-of-Function Is Detrimental to the Juvenile Host With Septic Shock, 2021-09-21

• Prognostic and predictive value of endothelial dysfunction biomarkers in sepsis-associated acute kidney injury: risk-stratified analysis from a prospective observational cohort of pediatric septic shock, 2023-07-03

• Glucocorticoid receptor polymorphisms and outcomes in pediatric septic shock, 2016-11-11

• Evaluating Demographic Data to Improve Confidence in Equity Analytics in a Children's Hospital, 2023-04-10

• Combining prognostic and predictive enrichment strategies to identify children with septic shock responsive to corticosteroids, 2016-03-22

• A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury, 2015-11-17

• Cardiopulmonary Resuscitation in Interfacility Transport: An International Report Using the Ground Air Medical Quality in Transport (GAMUT) Database, 2020-07-10

• PERSEVERE-II: Redefining the pediatric sepsis biomarker risk model with septic shock phenotype, 2016-12-27

• Transport Disposition Using Transport Risk Assessment in Pediatrics (TRAP) Score, 2012-03-23

• The pediatric sepsis biomarker risk model, 2012-10-01

• The Temporal Version of the Pediatric Sepsis Biomarker Risk Model, 2014-03-13

• Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1, 2023-02-03

• Enhanced disinfection with hybrid hydrogen peroxide fogging in a critical care setting, 2022-09-29

• ENDOTYPE TRANSITIONS DURING THE ACUTE PHASE OF PEDIATRIC SEPTIC SHOCK REFLECT CHANGING RISK AND TREATMENT RESPONSE, 2017-12-06

• Revisiting post-ICU admission fluid balance across pediatric sepsis mortality risk strata: A secondary analyses from a prospective observational cohort study, 2023-06-28

• Severe Acute Kidney Injury is Independently Associated with Mortality in Children with Septic Shock, 2020-02-11

• Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock, 2014-11-19

• Post-intensive care unit admission fluid balance and pediatric septic shock outcomes: A risk-stratified analysis, 2013-09-25

• Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model, 2019-11-13

• Hyperchloremia is associated with complicated course and mortality in pediatric patients with septic shock, 2017-10-23

• Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children, 2012-10-29