Dr. Steven Albelda, MD

• Pulmonary Disease

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• University Of Pennsylvania Perelman School Of Medicine

  Medical School, 1979

• GENE THERAPY FOR LUNG NEOPLASMS, 2011-10-07

• LOWER SERUM ENDOCAN LEVELS ARE ASSOCIATED WITH THE DEVELOPMENT OF ACUTE LUNG INJURY AFTER MAJOR TRAUMA, 2011-09-29

• Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms, 2018-02-16

• Luminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil ActivityIn Vivoand Serves as a Biomarker of Therapeutic Efficacy†, 2018-11-26

• Targeting Cardiac Fibrosis with Engineered T cells, 2019-09-11

• Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils, 2012-02-14

• Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors, 2023-08-22

• Mesothelin, a novel immunotherapy target for triple negative breast cancer, 2012-03-15

• Prevention of Alveolar Destruction and Airspace Enlargement in a Mouse Model of Pulmonary Lymphangioleiomyomatosis (LAM), 2012-10-03

• An NK-like CAR T cell transition in CAR T cell dysfunction, 2021-12-02

• The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cellsin vitroandin vivowith particular efficacy for small cell lung cancer, 2009-08-11

• Systemic Blockade of Transforming Growth Factor-ß (TGF-ß) Signaling Augments the Efficacy of Immunogene Therapy, 2008-12-15

• Mouse versus human neutrophils in cancer-a major knowledge gap, 2017-01-19

• Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity Without Severe Toxicity, 2013-11-12

• Current Advances in CAR T Cell Therapy for Malignant Mesothelioma, 2020-08-12

• CAR T cells producedin vivoto treat cardiac injury, 2022-01-06

• Advanced Glycation Endproducts on Stored Erythrocytes increase Endothelial Reactive Oxygen Species Generation through Interaction with RAGE, 2010-08-09

• CCL2 Blockade Augments Cancer Immunotherapy, 2009-12-22

• Inhibition of p300 impairs Foxp3+T-regulatory cell function and promotes anti-tumor immunity, 2013-08-18

• Tumor-promoting desmoplasia is disrupted by depleting FAP-expressing stromal cells, 2015-05-15

• Multifactorial T cell Hypofunction that is Reversible Can Limit the Efficacy of Chimeric Antibody Receptor-transduced Human T cells in Solid Tumors, 2014-06-11

• A Preclinical Model to Investigate the Role of Surgically-Induced Inflammation in Tumor Responses to Intraoperative Photodynamic Therapy, 2018-05-25

• Mesothelin-specific Chimeric Antigen Receptor mRNA-Engineered T cells Induce Anti-Tumor Activity in Solid Malignancies, 2013-12-19

• Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen Presenting Cell Features (Hybrid TANs) in Early-Stage Human Lung Cancer, 2016-06-30

• Junctional adhesion molecule-C (JAM-C) regulates polarized neutrophil transendothelial cell migrationin vivo, 2011-06-26

• Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer, 2016-10-17

• Monitoring Therapeutic Response to Anti-Fibroblast Activation Protein (FAP) CAR T Cells using [18F]AlF-FAPI-74, 2022-12-15

• Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer, 2019-02-13

• Bioanalytical techniques for detecting biomarkers of response to human asbestos exposure, 2015-06-18

• Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases, 2013-04-10

• Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells, 2022-08-22

• The timing of TGF-ß inhibition affects the generation of antigen-specific CD8+T Cells, 2013-07-17

• Surgical cytoreduction restores the antitumor efficacy of aListeria monocytogenesvaccine in malignant pleural mesothelioma, 2015-05-18

• Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients, 2016-08-05

• Expression of Interferon-ß Enhances Both Efficacy and Safety of Oncolytic Vesicular Stomatitis Virus for Therapy of Mesothelioma, 2009-09-22

• Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-ß type II receptor, 2011-09-12

• Thymidylate Synthase and Folyl-polyglutamate synthase (FPGS) Are Not Clinically Useful Markers of Response to Pemetrexed [Pem] in Patients with Malignant Pleural Mesothelioma [MPM], 2013-02-27

• Polarization of Tumor-Associated Neutrophil (TAN) Phenotype by TGF-ß: "N1” versus "N2” TAN, 2009-09-08

• Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells, 2022-09-03

• Surgical Inflammation Alters Immune Response to Intraoperative Photodynamic Therapy, 2023-09-11