Dr. Christine Lian, MD

• Dermatopathology

• Anatomic & Clinical Pathology

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• Histologic features of GVHD-associated angiomatosis: Insights into pathophysiology and treatment, 2020-01-08

• Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naive patient melanomas, 2015-06-09

• Loss of 5-hydroxymethylcytosine correlates with increasing morphologic dysplasia in melanocytic tumors, 2014-01-03

• Histopathologic Spectrum of Hypersensitivity Reactions Associated with anti-CD52 Therapy (Alemtuzumab), 2016-09-09

• Autoreactive CD8+T cells are restrained by an exhaustion-like program that is maintained by LAG3, 2022-05-26

• DNA methylation/hydroxymethylation in melanoma, 2017-05-30

• Inhibition of melanoma cell-intrinsic Tim-3 stimulates MAPK-dependent tumorigenesis, 2022-10-17

• ATF-3 expression inhibits melanoma growth by downregulating ERK and AKT pathways, 2020-12-09

• Distinct genetic profiles of extracranial and intracranial acral melanoma metastases, 2016-06-29

• HomozygousALOXE3Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi's Granuloma: The Consequences of Skin Barrier Dysfunction, 2015-09-09

• Melanoma cell-intrinsic PD-1 receptor functions promote tumor growth, 2015-09-10

• Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer, 2017-12-20

• Decrease of 5-Hydroxymethylcytosine in Rat Liver with Subchronic Exposure to Genotoxic Carcinogens Riddelliine and Aristolochic Acid, 2014-08-23

• The protective role of DOT1L in UV-induced melanomagenesis, 2018-01-17

• Longitudinal, 3D Imaging of Collagen Remodeling in Murine Hypertrophic ScarsIn Vivousing Polarization-sensitive Optical Frequency Domain Imaging, 2016-03-22

• Loss of NECTIN1 triggers melanoma dissemination upon local IGF1 depletion, 2022-10-13

• Solid Organ Transplant Graft-Versus-Host Disease in a Kidney/Pancreas Transplant Patient: Use of Chimerism Testing and a Rare Presentation of Cutaneous GVHD, 2022-03-09

• Cancer-germline antigen expression discriminates clinical outcome to CTLA-4 blockade, 2018-04-12

• Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats, 2008-10-17

• 5-Hydroxymethylcytosine Expression in Metastatic Melanoma versus Nodal Nevus in Sentine Lymph Node Biopsies, 2014-08-01

• Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation, 2022-08-09

• Melanoma Epigenetics: Novel Mechanisms, Markers, and Medicines, 2014-06-30

• The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution, 2022-06-02

• Development of a Patient-Derived 3D Immuno-Oncology Platform to Potentiate Immunotherapy Responses in Ascites-Derived Circulating Tumor Cells, 2023-08-16

• Regulation of 5-hydroxymethylcytosine by TET2 contributes to Squamous Cell Carcinoma tumorigenesis, 2021-10-23

• Chronic Rejection of Human Face Allografts, 2018-11-10

• Increased levels of circulating MMP3 correlate with severe rejection in face transplantation, 2018-10-08

• Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma, 2015-10-09

• LOSS OF 5-HYDROXYMETHYLCYTOSINE IS AN EPIGENETIC HALLMARK OF MELANOMA, 2012-09-14

• Nestin depletion induces melanoma matrix metalloproteinases and invasion, 2014-11-03

• Loss of the Epigenetic Mark, 5-hmC, in Psoriasis: Implications for Epidermal Stem Cell Dysregulation, 2019-12-11

• Cellular activation pathways and interaction networks in vascularized composite allotransplantation, 2023-05-17

• Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer, 2018-07-18

• Evolution of Delayed Resistance to Immunotherapy in a Melanoma Responder, 2021-05-03