Dr. Edward Ryan, MD

• Infectious Disease Medicine

• Internal Medicine

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Harvard Medical School

  Medical School, 1988

• Antigen-Specific Memory B-cell Responses to EnterotoxigenicEscherichia coliInfection in Bangladeshi Adults, 2014-04-24

• Systemic, Mucosal, and Memory Immune Responses following Cholera, 2021-10-27

• Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease, 2015-09-30

• Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain, 2021-12-02

• Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events, 2020-12-10

• Virus-like Particle Display ofVibrio cholerae O-Specific Polysaccharide as a Potential Vaccine against Cholera, 2022-02-16

• Evaluation of a Rapid Point-of-Care Multiplex Immunochromatographic Assay for the Diagnosis of Enteric Fever Kumar et al., 2020-06-10

• Cholera in pregnancy: Clinical and immunological aspects, 2015-08-14

• Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events., 2020-08-25

• Immunogenicity of a Killed Bivalent (O1 and O139) Whole Cell Oral Cholera Vaccine, Shanchol, in Haiti, 2014-05-01

• The Cholera Pandemic, Still with Us after Half a Century: Time to Rethink, 2011-01-25

• An assessment of potential biomarkers of environment enteropathy and its association with age and microbial infections among children in Bangladesh, 2021-04-22

• Missed opportunities for measles-mumps-rubella (MMR) vaccination among US pediatric international travelers, 2020-02-03

• Nano-Magnetic System For Rapid Diagnosis Of Acute Infection, 2017-11-14

• A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) ofV. choleraeO1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice, 2015-07-08

• Missed opportunities for MMR vaccination among departing U.S. adult travelers receiving pretravel health consultations, 2017-05-16

• Vibrio cholerae Isolation from Frozen Vomitus and Stool Samples, 2022-09-28

• Gut Microbiota and Development of Vibrio cholerae -Specific Long-Term Memory B Cells in Adults after Whole-Cell Killed Oral Cholera Vaccine, 2021-07-06

• Mucosal-Associated Invariant T (MAIT) cells are highly activated in duodenal tissue of humans withVibrio choleraeO1 infection: A preliminary report, 2022-05-12

• Coding-complete genomes of XBB.1.16, XBB.2.3, FL.4 (alias of XBB.1.9.1.4), and XBB.3 of SARS-CoV-2 Omicron isolated from Bangladesh, 2023-10-01

• Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults, 2016-06-16

• Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection againstVibrio choleraeO1 infection among household contacts of cholera patients in Bangladesh, 2018-04-23

• Estimating typhoid incidence from community-based serosurveys: a multicohort study, 2022-08-01

• HIV infection, pulmonary tuberculosis and COPD in rural Uganda: A cross-sectional study, 2017-12-19

• Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients, 2020-10-08

• Circulating Mucosal Associated Invariant T Cells Are Activated inVibrio choleraeO1 Infection and Associated with Lipopolysaccharide Antibody Responses, 2014-08-21

• Chemoproteomic profiling of host and pathogen enzymes active in cholera, 2016-02-22

• Scalable production and immunogenicity of a cholera conjugate vaccine, 2021-11-16

• Immune Responses to an Oral Cholera Vaccine in Internally Displaced Persons in South Sudan, 2016-10-24

• Use of a MAIT-Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model ofVibrio choleraeO1 Vaccination, 2022-08-24

• Structural basis for continued antibody evasion by the SARS-CoV-2 receptor-binding domain, 2022-01-21

• Natural Selection in a Bangladeshi Population from the Cholera-Endemic Ganges River Delta, 2013-07-03

• High Rates of Enteric Fever Diagnosis and Lower Burden of Culture-Confirmed Disease in Peri-urban and Rural Nepal, 2017-07-28

• Parenteral Vaccination with a Cholera Conjugate Vaccine Boosts Vibriocidal and Anti-OSP Responses in Mice Previously Immunized with an Oral Cholera Vaccine, 2021-04-19

• A Combination of Metagenomic and Cultivation Approaches Reveals Hypermutator Phenotypes within Vibrio cholerae -Infected Patients, 2021-08-24

• Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-SalmonellaIgA in Secretions of Peripheral Blood Lymphocytes in Patients in Dhaka, Bangladesh, 2013-07-11

• Typhoid Fever in Young Children in Bangladesh: Clinical Findings, Antibiotic Susceptibility Pattern and Immune Responses, 2015-04-07

• Longevity of memory B cells and antibodies, as well as the polarization of effector memory helper T cells, are associated with disease severity in patients with COVID-19 in Bangladesh, 2022-12-12

• Individuals with Le(a+b-) Blood Group Have Increased Susceptibility to SymptomaticVibrio choleraeO1 Infection, 2011-12-27

• Identifying Recent Cholera Infections Using a Multiplex Bead Serological Assay, 2022-10-26

• Factors Associated with Non-typhoidal Salmonella Bacteremia versus Typhoidal Salmonella Bacteremia in Patients Presenting for Care in an Urban Diarrheal Disease Hospital in Bangladesh, 2015-09-11

• Clinical Outcomes in Household Contacts of Patients with Cholera in Bangladesh, 2009-11-15

• Vibrio choleraeSerogroup O139: Isolation from Cholera Patients and Asymptomatic Household Family Members in Bangladesh between 2013 and 2014, 2015-11-12

• Test performance evaluation of SARS-CoV-2 serological assays, 2020-08-27

• 738. Comparison of Characteristics of US International Travelers Seeking Pretravel Health Consultations at US Global TravEpiNet Sites Before and During the COVID-19 Pandemic, 2021-12-04

• Cognate T and B cell interaction and association of follicular helper T cells with B cell responses inVibrio choleraeO1 infected Bangladeshi adults, 2018-12-21

• Analysis ofSalmonella entericaSerotype Paratyphi A Gene Expression in the Blood of Bacteremic Patients in Bangladesh, 2010-12-07

• Interferon-? and Proliferation Responses toSalmonella entericaSerotype Typhi Proteins in Patients withS. Typhi Bacteremia in Dhaka, Bangladesh, 2011-06-07

• Bivalent oral cholera vaccination induces a memory B cell response to theV. choleraeO1-polysaccharide antigen in Haitian adults, 2019-01-31

• 180. Alterations to the Gut Microbiomes and Acquisition of Bacteria Resistance Elements among US International Travelers, 2021-12-04

• Immune responses to O-specific polysaccharide (OSP) in North American adults infected withVibrio choleraeO1 Inaba, 2019-11-19

• What proportion of international travellers acquire a travel-related illness? A review of the literature, 2017-09-01

• The Effect of Vaccine Type and SARS-CoV-2 Lineage on Commercial SARS-CoV-2 Serologic and Pseudotype Neutralization Assays in mRNA Vaccine Recipients, 2022-03-21

• Induction of systemic, mucosal and memory antibody responses targetingVibrio choleraeO1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh, 2019-08-01

• Characteristics and preparation of the last-minute traveler: analysis of vaccine usage in the Global TravEpiNet Consortium, 2019-09-02

• A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever, 2016-09-08

• Identification of ImmunogenicSalmonella entericaSerotype Typhi Antigens Expressed in Chronic Biliary Carriers ofS.Typhi in Kathmandu, Nepal, 2013-08-01

• Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children, 2016-11-08

• Susceptibility toVibrio choleraeInfection in a Cohort of Household Contacts of Patients with Cholera in Bangladesh, 2008-04-09

• Meeting Cholera's Challenge to Haiti and the World: A Joint Statement on Cholera Prevention and Care, 2011-05-31

• Erratum to: Use of a MAIT-Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model ofVibrio choleraeO1 Vaccination, 2022-09-13

• Comparative Proteomic Analysis of the PhoP Regulon inSalmonella entericaSerovar Typhi Versus Typhimurium, 2009-09-10

• Cholera, 2012-06-30

• Single-Cell Analysis of the Plasmablast Response toVibrio choleraeDemonstrates Expansion of Cross-Reactive Memory B Cells Kauffman et al., 2016-12-20

• Informal Urban Settlements and Cholera Risk in Dar es Salaam, Tanzania, 2010-03-16

• High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic, 2012-09-11

• Comparison of the Performance of the TPTest, Tubex, Typhidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach, 2016-04-08

• SARS-CoV-2 viral load is associated with increased disease severity and mortality, 2020-10-30

• Defining Polysaccharide-Specific Antibody Targets against Vibrio cholerae O139 in Humans following O139 Cholera and following Vaccination with a Commercial Bivalent Oral Cholera Vaccine, and Evaluation of Conjugate Vaccines Targeting O139, 2021-07-07

• Humans Surviving Cholera Develop Antibodies against Vibrio cholerae O-Specific Polysaccharide That Inhibit Pathogen Motility Charles et al., 2020-11-17

• Morbidity and mortality due to shigella and enterotoxigenicEscherichia colidiarrhoea: the Global Burden of Disease Study 1990-2016, 2018-11-01

• Vibrio cholerae Sialidase-Specific Immune Responses Are Associated with Protection against Cholera, 2021-04-28

• Dynamics and significance of the antibody response to SARS-CoV-2 infection, 2020-07-20

• Cholera Toxin-Specific Memory B Cell Responses Are Induced in Patients with Dehydrating Diarrhea Caused byVibrio choleraeO1, 2008-10-01

• Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19 VIRULENCE, 2022-05-19

• In VivoExpression ofSalmonella entericaSerotype Typhi Genes in the Blood of Patients with Typhoid Fever in Bangladesh, 2011-12-13

• An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates, 2021-09-08

• Covishield vaccine induces robust immune responses in Bangladeshi adults, 2022-04-29

• Evaluation of an Electricity-free, Culture-based Approach for Detecting TyphoidalSalmonellaBacteremia during Enteric Fever in a High Burden, Resource-limited Setting, 2013-06-27

• Development of Shigella conjugate vaccines targetingShigella flexneri2a andS. flexneri3a using a simple platform-approach conjugation by squaric acid chemistry, 2023-07-01

• Immunologic Responses toVibrio choleraein Patients Co-Infected with Intestinal Parasites in Bangladesh, 2009-03-31

• Assessing antigen specific HLA-DR+ antibody secreting cell (DR+ASC) responses in whole blood in enteric infections using an ELISPOT technique, 2017-11-08

• Humoral signatures of protective and pathological SARS-CoV-2 infection in children, 2021-02-12

• Mass photometry: A powerful tool for carbohydrates-proteins conjugation monitoring and glycoconjugates molecular mass determination, 2023-07-01

• Immune responses to cholera in children, 2012-06-08

• Enabling clinicians to easily find location-based travel health recommendations-is innovation needed?, 2018-01-01

• Household Transmission ofVibrio choleraein Bangladesh, 2014-11-20

• Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-typeVibrio choleraeO1 El Tor Inaba in North American volunteers, 2018-04-06

• A Variant in Long Palate, Lung and Nasal Epithelium Clone 1 is Associated with Cholera in a Bangladeshi Population, 2009-02-12

• Isolation, purification, characterization and direct conjugation of the lipid A-free lipopolysaccharide ofVibrio choleraeO139, 2019-08-20

• Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae Weil et al., 2019-08-21

• Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, Bangladesh, 2022-01-04

• Conjugate Vaccines from Bacterial Antigens by Squaric Acid Chemistry: A Closer Look, 2017-03-23

• Diagnostics for invasiveSalmonellainfections: current challenges and future directions, 2015-04-30

• Transcutaneous Vaccination with Conjugate Typhoid Vaccine Vi-DT Induces Systemic, Mucosal, and Memory Anti-Polysaccharide Responses, 2020-07-27

• Development of a new dipstick (Cholkit) for rapid detection ofVibrio choleraeO1 in acute watery diarrheal stools, 2018-03-14

• Dried Blood Spots for MeasuringVibrio cholerae-specific Immune Responses, 2018-01-29

• Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19, 2022-07-21

• Estimating cholera incidence with cross-sectional serology, 2019-02-20

• Oral immunization with a probiotic cholera vaccine induces broad protective immunity againstVibrio choleraecolonization and disease in mice, 2019-05-31

• Transcutaneous immunization with a synthetic hexasaccharide-protein conjugate induces anti-Vibrio choleraelipopolysaccharide responses in mice, 2009-06-27

• Distinct Early Serological Signatures Track with SARS-CoV-2 Survival, 2020-09-15

• Defining endemic cholera at three levels of spatiotemporal resolution within Bangladesh, 2018-06-25

• Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen, 2020-02-20

• Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity Loos et al., 2020-09-02

• Systems approach to define humoral correlates of immunity toShigella, 2022-08-16

• A Comparison of Clinical and Immunologic Features in Children and Older Patients Hospitalized With Severe Cholera in Bangladesh, 2009-07-21

• Long-term sialidase-specific immune responses after natural infection with cholera: Findings from a longitudinal cohort study in Bangladesh, 2022-12-22

• Evaluation in Mice of a Conjugate Vaccine for Cholera Made fromVibrio choleraeO1 (Ogawa) O-Specific Polysaccharide, 2014-02-06

• Implications of acquired environmental enteric dysfunction for growth and stunting in infants and children living in low- and middle-income countries, 2015-10-23

• Impact of DNA Extraction Method on Variation in Human and Built Environment Microbial Community and Functional Profiles Assessed by Shotgun Metagenomics Sequencing, 2020-05-25

• Vibriocidal Titer and Protection From Cholera in Children, 2019-02-11

• Impact of Immunoglobulin Isotype and Epitope on the Functional Properties ofVibrio choleraeO-Specific Polysaccharide-Specific Monoclonal Antibodies, 2021-04-20

• Increased severity in patients presenting to hospital with diarrhea in Dhaka, Bangladesh Since emergence of the hybrid strain ofVibrio choleraeO1 is not unique to cholera patients, 2015-09-25

• Vibrio choleraegenomic diversity within and between patients, 2017-12-07

• Severe, Acute Watery Diarrhea in an Adult, 2010-11-30

• A Simple, Direct Conjugation of Bacterial O-SP-Core Antigens to Proteins: Development of Cholera Conjugate Vaccines, 2011-09-30

• Salmonellachronic carriage: epidemiology, diagnosis and gallbladder persistence, 2014-07-22

• Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses, 2020-08-20

• Antibody responses after COVID-19 infection in patients who are mildly symptomatic or asymptomatic in Bangladesh, 2020-12-01

• Application of In Vivo Induced Antigen Technology (IVIAT) toBacillus anthracis, 2008-03-19

• Comparison of clinical features and immunological parameters of patients with dehydrating diarrhoea infected with Inaba or Ogawa serotypes of Vibrio cholerae O1, 2013-07-16