Dr. Elazer Edelman, MD

• Cardiology

• Internal Medicine

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Brigham And Womens Hospital

  Fellowship Hospital, 1990

• Brigham And Womens Hospital

  Residency Hospital, 1987

• Harvard Medical School

  Medical School, 1983

• Luminal flow patterns dictate arterial drug deposition in stent-based delivery, 2008-09-26

• Impact of concomitant vasoactive treatment and mechanical left ventricular unloading in a porcine model of profound cardiogenic shock, 2020-03-18

• First Generation Bioresorbable Vascular Scaffolds: Disappearing Stents or Disappearing Evidence?, 2017-04-12

• An inverse method for mechanical characterization of heterogeneous diseased arteries using intravascular imaging, 2021-11-18

• Vascular Regeneration by Local Growth Factor Release Is Self-Limited By Microvascular Clearance, 2009-05-26

• Innervation Patterns May Limit Response to Endovascular Renal Denervation, 2014-09-16

• Analysis: Intravascular Devices with a Higher Risk of Polymer Emboli: The Need for Particulate Generation Testing, 2020-06-10

• Lesion Complexity Determines Arterial Drug Distribution After Local Drug Delivery, 2009-11-17

• Mechanical circulatory support device-heart hysteretic interaction can predict left ventricular end diastolic pressure, 2018-02-28

• Primary monocytes regulate endothelial cell survival through secretion of Angiopoietin-1 and activation of endothelial Tie2, 2011-01-27

• Stent elution rate determines drug deposition and receptor-mediated effects, 2012-05-26

• The role of scaffold microarchitecture in engineering endothelial cell immunomodulation, 2012-07-12

• Heparanase Regulates Thrombosis in Vascular Injury and Stent-Induced Flow Disturbance, 2012-04-24

• Atherosclerotic plaque behind the stent changes after bare-metal and drug-eluting stent implantation in humans: implications for late stent failure?, 2016-07-22

• Renal denervation for treatment of hypertension - will 2017 be the year of enlightenment?, 2017-04-07

• Hemodynamic consequences of a multilayer flow modulator in Aortic Dissection, 2019-06-17

• Understanding TAVR device expansion as it relates to morphology of the bicuspid aortic valve: A simulation study, 2021-05-17

• Morphometric analysis of the human common hepatic artery reveals a rich and accessible target for sympathetic liver denervation, 2022-01-26

• Calcified plaque modification alters local drug delivery in the treatment of peripheral atherosclerosis, 2017-09-01

• A novel lesional transcriptional signature separates atherosclerosis with and without diabetes in Yorkshire swine and humans, 2021-02-11

• Th2 cells are essential for modulation of vascular repair by allogeneic endothelial cells, 2009-12-24

• Treatment with chondroitin sulfate to modulate inflammation and atherogenesis in obesity, 2015-12-13

• A geometrically adaptable heart valve replacement, 2020-02-19

• Intravascular Ultrasound Guidance to Minimize the use of Iodine Contrast in Percutaneous Coronary Intervention: The MOZART Randomized Controlled Trial, 2014-10-15

• Viscoelastic Adhesive Mechanics of Aldehyde-Mediated Soft Tissue Sealants, 2008-09-19

• Acute Stent-Induced Endothelial Denudation: Biomechanical Predictors of Vascular Injury, 2021-10-15

• A soft robotic sleeve mimicking the haemodynamics and biomechanics of left ventricular pressure overload and aortic stenosis, 2022-09-26

• Structural Mechanics Predictions Relating to Clinical Coronary Stent Fracture in a 5 Year Period in FDA MAUDE Database, 2015-10-14

• Role of CABG in the management of obstructive coronary arterial disease in patients with diabetes mellitus, 2012-02-09

• From Nonclinical Research to Clinical Trials and Patient-registries: Challenges and Opportunities in Biomedical Research, 2017-08-31

• Implantation of healthy matrix-embedded endothelial cells rescues dysfunctional endothelium and ischemic tissue in liver engraftment, 2016-02-05

• Multimodal loading environment predicts bioresorbable vascular scaffolds' durability, 2020-10-29

• Leveraging device-arterial coupling to determine cardiac and vascular state, 2019-01-28

• Procedural and anatomical determinants of multi-electrode renal denervation efficacy - insights from preclinical models, 2019-07-15

• Intramuscular Drug Transport Under Mechanical Loading: Resonance Between Tissue Function and Uptake, 2009-02-03

• Thin-Capped Atheromata with Reduced Collagen Content in Pigs Develop in Coronary Arterial Regions Exposed to Persistently Low Endothelial Shear Stress, 2013-05-02

• Particulates from Hydrophilic-Coated Guiding Sheaths Embolize to the Brain, 2016-03-20

• Dynamic Modulation of Device-Arterial Coupling to Determine Cardiac Output and Vascular Resistance, 2020-04-13

• Defining drug and target protein distributions after stent-based drug release: durable versus deployable coatings, 2018-02-05

• Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis, 2013-04-08

• Dual targeted immunotherapy viain vivodelivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells, 2015-06-01

• Balloon-based drug coating delivery to the artery wall is dictated by coating micro-morphology and angioplasty pressure gradients, 2020-08-20

• Graphene-dendrimer nanostars for targeted macrophage overexpression of metalloproteinase 9 and hepatic fibrosis precision therapy, 2018-08-16

• Arterial Remodeling and Endothelial Shear Stress Exhibit Significant Longitudinal Heterogeneity along the Length of Coronary Plaques, 2017-05-18

• Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials, 2015-10-26

• Ultrasound-guided percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model, 2012-07-15

• Tuning Adhesion Failure Strength For Tissue-Specific Applications, 2010-07-23

• Stent Thrombogenicity Early in High Risk Interventional Settings is Driven by Stent Design and Deployment, and Protected by Polymer-Drug Coatings, 2011-03-21

• Pathology of Endovascular Stents, 2016-05-19

• A Domain Enriched Deep Learning Approach to Classify Atherosclerosis using Intravascular Ultrasound Imaging, 2020-06-15

• The role of aortic compliance in determination of coarctation severity: lumped parameter modeling,in vitrostudy and clinical evaluation, 2015-10-26

• Sex differences in the outcomes of stent implantation in mini-swine model, 2018-01-29

• Vascular Lesion-Specific Drug Delivery Systems JACCState-of-the-Art Review, 2021-05-18

• Fracture in Drug-Eluting Stents Increases Focal Intimal Hyperplasia in the Atherosclerosed Rabbit Iliac Artery, 2018-09-23

• Revascularization for coronary artery disease in diabetes mellitus: Angioplasty, stents and coronary artery bypass grafting, 2010-11-16

• A Novel Algorithm to Quantify Coronary Remodeling Using Inferred Normal Dimensions, 2015-10-01

• Endovascular Drug Delivery and Drug Elution Systems: First principles, 2016-06-21

• In vivoandin vitroevaluation of a biodegradable magnesium vascular stent designed by shape optimization strategy, 2019-08-05

• Structural Biomechanics Modulate Intramuscular Distribution of Locally Delivered Drugs, 2008-08-15

• Chondroitin Sulphate Attenuates Atherosclerosis in ApoE Knockout Mice Involving Cellular Regulation of the Inflammatory Response, 2018-06-06

• Vascular tissue engineering: progress, challenges, and clinical promise, 2018-03-01

• Ultra-hydrophilic stent platforms promote early vascular healing and minimise late tissue response: a potential alternative to second-generation drug-eluting stents, 2017-04-20

• The Engagement of the Medical Technology Sector with Society at Large, 2017-04-12

• Impact of flow pulsatility on arterial drug distribution in stent-based therapy, 2013-03-27

• Diffusion-Limited Binding Explains Binary Dose Response for Local Arterial and Tumor Drug Delivery, 2009-03-31

• Attenuation of Inflammation and Expansive Remodeling by Valsartan Alone or in Combination with Simvastatin in High-Risk Coronary Atherosclerotic Plaques, 2008-08-05

• Topographic pattern of valve calcification: a new determinant of disease severity in aortic valve stenosis, 2017-12-13

• NF-?B Activity in Endothelial Cells Is Modulated by Cell Substratum Interactions and Influences Chemokine-Mediated Adhesion of Natural Killer Cells, 2010-03-18

• Comparison of the Absorbable Polymer Sirolimus Eluting Stent (MiStent) to the Durable Polymer Everolimus Eluting Stent (Xience) (From the DESSOLVE I/II and ISAR-TEST-4 studies), 2015-12-07

• Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype, 2015-12-16

• Stromal Endothelial Cells Directly Influence Cancer Progression, 2011-01-19

• Substratum interactions determine immune response to allogeneic transplants of endothelial cells, 2022-08-08

• Dabigatran and Rivaroxaban Use in Atrial Fibrillation Patients on Hemodialysis, 2015-01-16

• Optimal Control of Blood Glucose: The Diabetic Patient or the Machine?, 2010-04-14

• Enhancing physiologic simulations using supervised learning on coarse mesh solutions, 2015-03-06

• In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging, 2011-08-21

• Modifications of microvascular EC surface modulate phototoxicity of a porphycene anti-ICAM-1 immunoconjugate; therapeutic implications, 2013-07-26

• Function and Mode of Regulation of Endothelial Major Histocompatibility Complex Class II, 2010-03-18

• Osterix-mCherry Expression Allows For Early Bone Detection In A Calvarial Defect Model, 2019-11-04

• Single cell analysis of the normal mouse aorta reveals functionally distinct endothelial cell populations, 2019-05-31

• Elevated Fibroblast Growth Factor-2 Increases Tumor Necrosis Factor-a Induced Endothelial Cell Death in High Glucose, 2010-03-01

• A new integrative approach to assess aortic stenosis burden and predict objective functional improvement after TAVR, 2023-03-02

• Clinician-Investigators as Translational Bioscientists: Shaping a Seamless Identity, 2012-05-23

• Anti-Atherosclerotic Therapy Based on Botanicals, 2015-10-28

• Constraining OCT with Knowledge of Device Design Enables High Accuracy Hemodynamic Assessment of Endovascular Implants, 2016-02-23

• THROMBUS CAUSES FLUCTUATIONS IN ARTERIAL DRUG DELIVERY FROM INTRAVASCULAR STENTS, 2008-07-25

• Regulation of dendrimer:dextran material performance by altered tissue microenvironment in inflammation and neoplasia, 2015-01-28

• Effect of working environment and procedural strategies on mechanical performance of bioresorbable vascular scaffolds, 2018-10-17

• Natural Tissue Microenvironmental Conditions Modulate Adhesive Material Performance, 2012-10-18

• Application of Arterial Hemodynamics to Clinical Practice: A Testament to Medical Science in London, 2018-05-18

• Taking Paclitaxel Coated Balloons to a Higher Level: predicting coating dissolution kinetics, tissue retention and dosing dynamics, 2019-08-17

• Augmentation of post-swelling surgical sealant potential of adhesive hydrogels, 2010-09-28

• Optimized computer-aided segmentation and 3D reconstruction using intracoronary optical coherence tomography, 2018-05-24

• Quantification of Thrombus Formation in Malapposed Coronary Stents Deployedin-vitroThrough Imaging Analysis, 2018-02-09

• Optimizing glutaraldehyde-fixed tissue heart valves with chondroitin sulfate hydrogel for endothelialization and shield against deterioration, 2018-03-20

• RAPAMYCIN ACTIVATES TGF RECEPTOR INDEPENDENTLY OF ITS LIGAND: IMPLICATIONS FOR ENDOTHELIAL DYSFUNCTION., 2018-02-16

• Mechanisms of Tissue Uptake and Retention in Zotarolimus-Coated Balloon Therapy, 2013-04-12

• Sustained Efficacy and Arterial Drug Retention by a Fast Drug Eluting Cross-Linked Fatty Acid Coronary Stent Coating, 2015-08-28

• Matrix-Embedded Endothelial Cells Attain a Progenitor-Like Phenotype, 2017-07-20

• Luminal Flow Amplifies Stent-Based Drug Deposition in Arterial Bifurcations, 2009-12-02

• Assessment of the Angiogenic Potential of 2-Deoxy-D-Ribose Using a Novelin vitro3D Dynamic Model in Comparison With Establishedin vitroAssays, 2020-01-17

• 3D matrix embedding inhibits cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis of human endothelial cells, 2017-12-03

• Regulation of Heparanase Expression in Coronary Artery Disease in Diabetic, Hyperlipidemic Swine, 2010-09-18

• Ventricular stroke work and vascular impedance refine the characterization of patients with aortic stenosis, 2019-09-11

• Elimination of Trans-coarctation Pressure Gradients Has No Impact on Left Ventricular Function or Aortic Shear Stress Post Intervention in Patients with Mild Coarctation, 2016-09-26

• Arterial microanatomy determines the success of energy-based renal denervation in controlling hypertension, 2015-04-29

• Validation study to determine the accuracy of central blood pressure measurement using the SphygmoCor XCEL cuff device in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, 2021-05-04

• Could antiretrovirals be treating EBV in MS? A case report, 2018-02-27

• Hydrogel Nanocomposites with Independently Tunable Rheology and Mechanics, 2017-03-09

• Engineered arterial models to correlate blood flow to tissue biological response, 2012-03-29

• A Tunable Delivery Platform to Provide Local Chemotherapy for Pancreatic Ductal Adenocarcinoma, 2016-03-31

• Hysteretic device characteristics indicate cardiac contractile state for guiding mechanical circulatory support device use, 2021-12-20

• Importance of Receptor-targeted Systems in the Battle Against Atherosclerosis, 2015-10-28

• Tubular Bridges for Bronchial Epithelial Cell Migration and Communication, 2010-01-28

• Heparanase Alters Arterial Structure, Mechanics and Repair Following Endovascular Stenting in Mice, 2008-12-18

• Models of Human Vascular Disease: Is There an Animal of La Mancha? Modelos de la enfermedad vascular humana: ¿hay un animal de La Mancha?, 2015-10-28

• Drug deposition in coronary arteries with overlapping drug-eluting stents, 2016-07-16

• Characterization of Star Adhesive Sealant Based On PEG:Dextran Hydrogels, 2009-08-11

• miRNAs in atherosclerotic plaque initiation, progression, and rupture, 2015-03-11

• Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1000 patients with hypertension, 2018-05-20

• Efficacy of a Device to Narrow the Coronary Sinus in Refractory Angina, 2015-02-05

• The evolution of endothelial regulatory paradigms in cancer biology and vascular repair, 2011-12-05

• Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk, 2017-11-22

• Coronary artery disease and diabetes mellitus, 2014-06-10

• Pheochromocytoma-Induced Cardiomyopathy is Modulated by the Synergistic Effects of Cell-Secreted Factors Mobine. Cell-Secreted Factors in Pheo-Induced CM, 2009-02-10

• Natural History of Experimental Coronary Atherosclerosis and Vascular Remodeling In Relation to Endothelial Shear Stress: A Serial,In VivoIntravascular Ultrasound Study, 2010-05-03

• Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific Adhesion, 2009-09-04

• Catheter-based renal denervation in hypertension: heading for new shores, 2018-05-17

• A Mechanical Approach for Smooth Surface Fitting to Delineate Vessel Walls in Optical Coherence Tomography Images, 2018-11-29

• Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse, 2015-05-27

• Smooth muscle cells orchestrate the endothelial cell response to flow and injury, 2010-05-10

• Synergistic Effect of Local Endothelial Shear Stress and Systemic Hypercholesterolemia on Coronary Atherosclerotic Plaque Progression and Composition in Pigs, 2013-10-11