Dr. Rani George, MD

• Pediatric Hematology & Oncology

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• Boston Children's Hospital/dana-farber Cancer Institute

  Fellowship Hospital

• Boston Children's Hospital/dana-farber Cancer Institute, Pediatric Hematology -oncology

  Fellowship Hospital

• Harvard Medical School, Pathology

  Fellowship Hospital

• Boston Combined Residency Program (bcrp), Pediatrics

  Residency Hospital

• Boston Combined Residency Program, Boston Children's Hospital/boston Medical Center

  Residency Hospital

• The Royal Victoria Infirmary , Newcastle-upon-tyne

  Residency Hospital

• John F. Kennedy Memorial Medical Center

  Internship Hospital

• A.m. Dogliotti College Of Medicine, University Of Liberia

  Medical School

• Am Dogliotti College Of Medicine, University Of Liberia

  Medical School, 1986

• Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis, 2012-03-20

• Cbx3/HP1? deficiency confers enhanced tumor-killing capacity on CD8+T cells, 2017-02-21

• TheALKF1174Lmutation potentiates the oncogenic activity of MYCN in neuroblastoma, 2012-07-10

• Super-enhancer-driven Transcriptional Dependencies in Cancer, 2017-04-12

• Giotto: a toolbox for integrative analysis and visualization of spatial expression data, 2021-03-08

• Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma, 2010-10-15

• CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation, 2019-04-15

• mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis, 2018-09-19

• Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes, 2022-09-22

• Genome-Wide Analysis of Neuroblastomas using High-Density Single Nucleotide Polymorphism Arrays, 2007-02-28

• Targeting ALK: the ten lives of a tumor, 2015-12-14

• Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK), 2018-04-24

• Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib inALK-mutated neuroblastoma, 2014-08-19

• Mutations that disrupt PHOXB interaction with the neuronal calcium sensor HPCAL1 impede cellular differentiation in neuroblastoma, 2013-07-22

• ALK inhibitor resistance inALKF1174L-driven neuroblastoma is associated with AXL activation and induction of EMT, 2015-11-30

• Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy, 2009-11-16

• Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors, 2017-12-21

• Synergistic Anti-Tumor Effect of Combining Selective CDK7 and BRD4 Inhibition in Neuroblastoma, 2022-01-27

• Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration, 2021-07-13

• Comparison of Primary Neuroblastoma Tumors and Derivative Early-Passage Cell Lines Using Genome-Wide Single Nucleotide Polymorphism Array Analysis, 2009-05-12

• Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor, 2019-12-20

• CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription inMYCN-Driven Cancer, 2014-11-06

• BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells, 2019-08-07

• JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma, 2019-07-25

• MYCNamplification andATRXmutations are incompatible in neuroblastoma, 2020-02-14

• Phase I Study of Decitabine with Doxorubicin and Cyclophosphamide in Children with Neuroblastoma and Other Solid Tumors: A Children's Oncology Group Study, 2011-01-11

• Distinct Neuroblastoma-associated Alterations ofPHOX2BImpair Sympathetic Neuronal Differentiation in Zebrafish Models, 2013-06-06

• Emerging importance of ALK in neuroblastoma, 2011-09-16

• Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras, 2020-03-05

• Seek and Ye Shall Find: Subclonal Anaplastic Lymphoma Kinase Mutations, 2015-09-11