Dr. Vijay Sankaran, MD

• Pediatric Hematology & Oncology

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• Harvard University / School Of Psychology

  Medical School

• Dana-farber Cancer Institute/boston Children's Hospital, Pediatric Hematology/oncology

  Fellowship Hospital, 2015

• Boston Children's Hospital/boston Medical Center, Pediatrics

  Residency Hospital, 2013

• Harvard Medical School

  Medical School, 2010

• COVID-19 Presenting with Autoimmune Hemolytic Anemia in the Setting of Underlying Immune Dysregulation, 2020-06-03

• Hacking hematopoiesis - emerging tools for examining variant effects, 2023-02-24

• Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis, 2013-03-07

• A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia, 2022-12-15

• Clonal hematopoiesis in sickle cell disease, 2022-02-15

• Developmentally-Faithful and Effective Human Erythropoiesis in Immunodeficient andKitMutant Mice, 2017-07-19

• Development of autologous blood cell therapies, 2016-06-21

• Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis, 2016-07-01

• Topological control of cytokine receptor signaling induces differential effects in hematopoiesis, 2019-05-23

• The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6, 2016-08-10

• A unified model of human hemoglobin switching through single-cell genome editing, 2021-08-17

• Inherited Causes of Clonal Hematopoiesis in 97,691 TOPMed Whole Genomes, 2020-10-14

• Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis, 2019-05-09

• Perspectives of Rare Disease Experts on Newborn Genome Sequencing Perspectives of Rare Disease Experts on Newborn Genome Sequencing, 2023-05-08

• Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells, 2015-10-22

• Developmental and species-divergent globin switching are driven by BCL11A, 2009-08-05

• Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits, 2016-06-02

• Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research, 2018-03-22

• Advances in the understanding of haemoglobin switching, 2010-03-01

• Common a-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease, 2018-03-28

• In The Blood: Connecting Variant to Function In Human Hematopoiesis, 2020-06-10

• Interrogation of human hematopoiesis at single-cell and single-variant resolution, 2019-03-11

• Altered Chromatin Occupancy of Master Regulators Underlies Evolutionary Divergence in the Transcriptional Landscape of Erythroid Differentiation, 2014-12-18

• Shared and distinct genetic etiologies for different types of clonal hematopoiesis, 2023-09-08

• Variant to function mapping at single-cell resolution through network propagation, 2022-06-06

• Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing, 2021-10-11

• Emerging Cellular and Gene Therapies for Congenital Anemias, 2016-10-28

• Macrothrombocytopenia associated with a rareGFI1Bmissense variant confounding the presentation of immune thrombocytopenia, 2019-06-17

• Lineage Tracing In Humans Enabled By Mitochondrial Mutations And Single Cell Genomics, 2019-02-28

• Longitudinal single-cell dynamics of chromatin accessibility and mitochondrial mutations in chronic lymphocytic leukemia mirror disease history, 2021-12-01

• Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation, 2020-01-20

• Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia, 2020-10-21

• Deciphering transcriptional and functional heterogeneity in hematopoiesis with single-cell genomics, 2021-07-01

• The Polygenic and Monogenic Basis of Blood Traits and Diseases, 2020-09-03

• Thrombopoietin: tickling the HSC's fancy, 2017-11-30

• Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells, 2020-08-12

• Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations, 2022-02-24

• Mapping Transcriptomic Vector Fields of Single Cells, 2022-02-01

• The genetics of human hematopoiesis and its disruption in disease, 2019-07-17

• Uridine-responsive epileptic encephalopathy due to inherited variants inCAD: A Tale of Two Siblings C. M. McGrawet al., 2021-01-26

• Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling, 2020-08-12

• Unraveling Hematopoiesis Through the Lens of Genomics, 2020-09-17

• Rb and hematopoiesis: stem cells to anemia, 2008-09-08

• Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis, 2018-03-15

• Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis, 2015-02-05

• Structural variation across 138,134 samples in the TOPMed consortium, 2023-01-25

• Cellular barcoding to decipher clonal dynamics in disease, 2022-10-14

• Functional dissection of inherited non-coding variation influencing multiple myeloma risk, 2022-01-10

• Patchwork Cancer Predisposition, 2022-04-01

• Long-Term Patient-Customized Therapy for a PathogenicEPOMutation, 2020-11-09

• Scalable, multimodal profiling of chromatin accessibility, gene expression, and protein levels in single cells, 2021-06-03

• Variant to function mapping at single-cell resolution through network propagation, 2022-01-24

• Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort., 2019-02-06

• Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation, 2010-11-07

• Anemia: Progress in molecular mechanisms and therapy, 2015-05-29

• Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells, 2023-06-29

• Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk, 2022-12-13

• Correction of Sickle Cell Disease in Adult Mice by Interference with Fetal Hemoglobin Silencing, 2011-10-13

• Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations, 2020-09-03

• Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis, 2019-06-11

• Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility, 2023-02-15

• Functional Selectivity in Cytokine Signaling Revealed Through a PathogenicEPOMutation, 2017-03-09

• Structural variation across 138,134 samples in the TOPMed consortium, 2023-02-03

• Regulation of the fetal hemoglobin silencing factor BCL11A, 2016-03-09

• A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology, 2023-08-18

• Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction, 2020-04-17

• Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types, 2022-01-31

• Advances in Understanding Erythropoiesis: Evolving Perspectives, 2016-02-05

• Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells, 2020-10-14

• Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion, 2016-06-02

• Familial thrombocytopenia due to a complex structural variant resulting in aWAC-ANKRD26fusion transcript, 2021-04-15

• Altered translation of GATA1 in Diamond-Blackfan anemia, 2014-06-22