Dr. Richelle Charles, MD

• Infectious Disease Medicine

• Internal Medicine

*Healthgrades does not verify qualifications for medical specialties. Please verify your provider's specialty and qualifications directly with your provider and applicable medical board.

• Johns Hopkins School Of Medicine

  Medical School, 2003

• Induction of systemic, mucosal and memory antibody responses targetingVibrio choleraeO1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh, 2019-08-01

• Transcutaneous Vaccination with Conjugate Typhoid Vaccine Vi-DT Induces Systemic, Mucosal, and Memory Anti-Polysaccharide Responses, 2020-07-27

• Vibrio choleraegenomic diversity within and between patients, 2017-12-07

• Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection againstVibrio choleraeO1 infection among household contacts of cholera patients in Bangladesh, 2018-04-23

• Parenteral Vaccination with a Cholera Conjugate Vaccine Boosts Vibriocidal and Anti-OSP Responses in Mice Previously Immunized with an Oral Cholera Vaccine, 2021-04-19

• Circulating Mucosal Associated Invariant T Cells Are Activated inVibrio choleraeO1 Infection and Associated with Lipopolysaccharide Antibody Responses, 2014-08-21

• Covishield vaccine induces robust immune responses in Bangladeshi adults, 2022-04-29

• Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease, 2015-09-30

• Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19, 2022-07-21

• Identification of ImmunogenicSalmonella entericaSerotype Typhi Antigens Expressed in Chronic Biliary Carriers ofS.Typhi in Kathmandu, Nepal, 2013-08-01

• Defining Polysaccharide-Specific Antibody Targets against Vibrio cholerae O139 in Humans following O139 Cholera and following Vaccination with a Commercial Bivalent Oral Cholera Vaccine, and Evaluation of Conjugate Vaccines Targeting O139, 2021-07-07

• Nano-Magnetic System For Rapid Diagnosis Of Acute Infection, 2017-11-14

• Dynamics and significance of the antibody response to SARS-CoV-2 infection, 2020-07-20

• Salmonellachronic carriage: epidemiology, diagnosis and gallbladder persistence, 2014-07-22

• Typhoid Fever in Young Children in Bangladesh: Clinical Findings, Antibiotic Susceptibility Pattern and Immune Responses, 2015-04-07

• Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults, 2016-06-16

• COVID-19 neutralizing antibodies predict disease severity and survival, 2020-12-15

• Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity Loos et al., 2020-09-02

• A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) ofV. choleraeO1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice, 2015-07-08

• Humans Surviving Cholera Develop Antibodies against Vibrio cholerae O-Specific Polysaccharide That Inhibit Pathogen Motility Charles et al., 2020-11-17

• Evaluation of a Typhoid/Paratyphoid Diagnostic Assay (TPTest) Detecting Anti-SalmonellaIgA in Secretions of Peripheral Blood Lymphocytes in Patients in Dhaka, Bangladesh, 2013-07-11

• Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Juba, South Sudan: a population-based study, 2021-03-12

• A Simple, Direct Conjugation of Bacterial O-SP-Core Antigens to Proteins: Development of Cholera Conjugate Vaccines, 2011-09-30

• Development of Shigella conjugate vaccines targetingShigella flexneri2a andS. flexneri3a using a simple platform-approach conjugation by squaric acid chemistry, 2023-07-01

• Bivalent oral cholera vaccination induces a memory B cell response to theV. choleraeO1-polysaccharide antigen in Haitian adults, 2019-01-31

• Distinct Early Serological Signatures Track with SARS-CoV-2 Survival, 2020-09-15

• Estimating typhoid incidence from community-based serosurveys: a multicohort study, 2022-08-01

• In VivoExpression ofSalmonella entericaSerotype Typhi Genes in the Blood of Patients with Typhoid Fever in Bangladesh, 2011-12-13

• Systemic, Mucosal, and Memory Immune Responses following Cholera, 2021-10-27

• Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients, 2020-10-08

• Antibody responses after COVID-19 infection in patients who are mildly symptomatic or asymptomatic in Bangladesh, 2020-12-01

• Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-typeVibrio choleraeO1 El Tor Inaba in North American volunteers, 2018-04-06

• Interferon-? and Proliferation Responses toSalmonella entericaSerotype Typhi Proteins in Patients withS. Typhi Bacteremia in Dhaka, Bangladesh, 2011-06-07

• Structural basis for continued antibody evasion by the SARS-CoV-2 receptor-binding domain, 2022-01-21

• Disparities in SARS-CoV-2 Infection by Race, Ethnicity, Language, and Social Vulnerability: Evidence from a Citywide Seroprevalence Study in Massachusetts, USA, 2023-01-18

• Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19 VIRULENCE, 2022-05-19

• Comparative Proteomic Analysis of the PhoP Regulon inSalmonella entericaSerovar Typhi Versus Typhimurium, 2009-09-10

• A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever, 2016-09-08

• Evaluation in Mice of a Conjugate Vaccine for Cholera Made fromVibrio choleraeO1 (Ogawa) O-Specific Polysaccharide, 2014-02-06

• Vibrio cholerae Sialidase-Specific Immune Responses Are Associated with Protection against Cholera, 2021-04-28

• Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae Weil et al., 2019-08-21

• Single-Cell Analysis of the Plasmablast Response toVibrio choleraeDemonstrates Expansion of Cross-Reactive Memory B Cells Kauffman et al., 2016-12-20

• Impact of Immunoglobulin Isotype and Epitope on the Functional Properties ofVibrio choleraeO-Specific Polysaccharide-Specific Monoclonal Antibodies, 2021-04-20

• Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, Bangladesh, 2022-01-04

• Immune responses to O-specific polysaccharide (OSP) in North American adults infected withVibrio choleraeO1 Inaba, 2019-11-19

• Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain, 2021-12-02

• Immunogenicity of a Killed Bivalent (O1 and O139) Whole Cell Oral Cholera Vaccine, Shanchol, in Haiti, 2014-05-01

• Development of a new dipstick (Cholkit) for rapid detection ofVibrio choleraeO1 in acute watery diarrheal stools, 2018-03-14

• Identifying Recent Cholera Infections Using a Multiplex Bead Serological Assay, 2022-10-26

• Defining endemic cholera at three levels of spatiotemporal resolution within Bangladesh, 2018-06-25

• Test performance evaluation of SARS-CoV-2 serological assays, 2020-08-27

• An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates, 2021-09-08

• Evolutionary consequences of intra-patient phage predation on microbial populations, 2014-08-26

• Scalable production and immunogenicity of a cholera conjugate vaccine, 2021-11-16

• Evaluation of a Rapid Point-of-Care Multiplex Immunochromatographic Assay for the Diagnosis of Enteric Fever Kumar et al., 2020-06-10

• Longevity of memory B cells and antibodies, as well as the polarization of effector memory helper T cells, are associated with disease severity in patients with COVID-19 in Bangladesh, 2022-12-12

• COVID-19 neutralizing antibodies predict disease severity and survival, 2020-10-20

• Analysis ofSalmonella entericaSerotype Paratyphi A Gene Expression in the Blood of Bacteremic Patients in Bangladesh, 2010-12-07

• Comparison of the Performance of the TPTest, Tubex, Typhidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach, 2016-04-08

• Long-term sialidase-specific immune responses after natural infection with cholera: Findings from a longitudinal cohort study in Bangladesh, 2022-12-22

• The Effect of Vaccine Type and SARS-CoV-2 Lineage on Commercial SARS-CoV-2 Serologic and Pseudotype Neutralization Assays in mRNA Vaccine Recipients, 2022-03-21